DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway

[1] Mizushima N(2008)Autophagy fights disease through cellular self-digestion Nature 451 1069-1075

[2] Yang Z(2010)Eaten alive: a history of macroautophagy Nat Cell Biol 12 814-822

[3] Klionsky DJ(1998)Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase J Biol Chem 273 23758-23763

[4] Samari HR(2005)The coordinate regulation of the p53 and mTOR pathways in cells Proc Natl Acad Sci U S A 102 8204-8209

[5] Seglen PO(2005)Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy Cell 122 927-939

[6] Feng Z(2013)The pro-survival role of autophagy depends on Bcl-2 under nutrition stress conditions PLoS One 8 e63232-960

[7] Pattingre S(2000)Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain Biochem Biophys Res Commun 279 955-1657

[8] Xu HD(2002)The phosphoinositide 3-kinase pathway Science 296 1655-13

[9] Lopaczynski W(2000)A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells Cancer Res 60 3504-7777

[10] Terry C(1998)Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway Proc Natl Acad Sci U S A 95 7772-371

[1] Mizushima N(2008)Autophagy fights disease through cellular self-digestion Nature 451 1069-1075

[2] Yang Z(2010)Eaten alive: a history of macroautophagy Nat Cell Biol 12 814-822

[3] Klionsky DJ(1998)Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase J Biol Chem 273 23758-23763

[4] Samari HR(2005)The coordinate regulation of the p53 and mTOR pathways in cells Proc Natl Acad Sci U S A 102 8204-8209

[5] Seglen PO(2005)Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy Cell 122 927-939

[6] Feng Z(2013)The pro-survival role of autophagy depends on Bcl-2 under nutrition stress conditions PLoS One 8 e63232-960

[7] Pattingre S(2000)Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain Biochem Biophys Res Commun 279 955-1657

[8] Xu HD(2002)The phosphoinositide 3-kinase pathway Science 296 1655-13

[9] Lopaczynski W(2000)A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells Cancer Res 60 3504-7777

[10] Terry C(1998)Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway Proc Natl Acad Sci U S A 95 7772-371