Comprehensive analysis of the characteristics and treatment outcomes of patients with non-small cell lung cancer treated with anti-PD-1 therapy in real-world practice

被引:0
作者
Beung-Chul Ahn
Kyoung-Ho Pyo
Chun-Feng Xin
Dongmin Jung
Hyo Sup Shim
Chang Young Lee
Seong Yong Park
Hong In Yoon
Min Hee Hong
Byoung Chul Cho
Hye Ryun Kim
机构
[1] Yonsei University College of Medicine,Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center
[2] Yonsei University College of Medicine,Severance Biomedical Science Institute
[3] Yonsei University College of Medicine,Department of Pathology, Severance Hospital
[4] Yonsei University College of Medicine,Department of Thoracic and Cardiovascular Surgery
[5] Yonsei University College of Medicine,Department of Radiation Oncology, Yonsei Cancer Center
来源
Journal of Cancer Research and Clinical Oncology | 2019年 / 145卷
关键词
Immunotherapy; Non-small cell lung cancer; Real-world setting; PD-1; Survival;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1613 / 1623
页数:10
相关论文
共 68 条
[11]  
Proverbs-Singh TA(2018)Association of immune-related adverse events with nivolumab efficacy in non-small cell lung cancer JAMA Oncol 4 374-378
[12]  
Postow MA(2016)Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer Oncoimmunology 5 e1231292-1380
[13]  
Fujimoto D(2008)Lung cancer N Engl J Med 359 1367-567
[14]  
Garassino MC(2014)Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients Nature 515 563-1550
[15]  
Garcia S(2016)Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial Lancet 387 1540-1368
[16]  
Garon EB(2012)Prognostic models to predict survival in non-small-cell lung cancer patients treated with first-line paclitaxel and carboplatin with or without bevacizumab J Thorac Oncol 7 1361-e358
[17]  
Gauvain C(2018)Real-world efficacy and safety of nivolumab for advanced non-small-cell lung cancer: a retrospective multicenter analysis Clin Lung Cancer 19 e349-407
[18]  
Haratani K(2017)Checkpoint inhibitors in metastatic EGFR-mutated non-small cell lung cancer-a meta-analysis J Thorac Oncol 12 403-15046
[19]  
Hasan Ali O(2016)The prevalence and clinicopathological features of programmed death-ligand 1 (PD-L1) expression: a pooled analysis of literatures Oncotarget 7 15033-589
[20]  
Herbst RS(2018)Pembrolizumab (pembro) versus platinum-based chemotherapy (chemo) as first-line therapy for advanced/metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 1%: open-label, phase 3 KEYNOTE-042 study J Clin Oncol 36 abstr LBA4-1833