Outcome of severe lactic acidosis associated with metformin accumulation

[1] Jones GC(2003)Contraindications to the use of metformin BMJ 326 4-5

[2] Macklin JP(2002)Metformin: an update Ann Intern Med 137 25-33

[3] Alexander WD(2009)Metformin-associated lactic acidosis: a prognostic and therapeutic study Crit Care Med 37 2191-2196

[4] Kirpichnikov D(2002)Metformin-associated lactic acidosis: case reports and literature review J Nephrol 15 398-402

[5] McFarlane SI(2003)Mitochondrial metabolism and type-2 diabetes: a specific target of metformin Diabetes Metab 29 6S88-94

[6] Sowers JR(2008)Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro Toxicol Appl Pharmacol 233 203-210

[7] Seidowsky A(2010)Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5 J Endocrinol 205 97-106

[8] Nseir S(2010)Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice Diabetologia 53 1472-1481

[9] Houdret N(2008)Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP Diabetes 57 306-314

[10] Fourrier F(2003)Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysis Arch Intern Med 163 2594-2602

[1] Jones GC(2003)Contraindications to the use of metformin BMJ 326 4-5

[2] Macklin JP(2002)Metformin: an update Ann Intern Med 137 25-33

[3] Alexander WD(2009)Metformin-associated lactic acidosis: a prognostic and therapeutic study Crit Care Med 37 2191-2196

[4] Kirpichnikov D(2002)Metformin-associated lactic acidosis: case reports and literature review J Nephrol 15 398-402

[5] McFarlane SI(2003)Mitochondrial metabolism and type-2 diabetes: a specific target of metformin Diabetes Metab 29 6S88-94

[6] Sowers JR(2008)Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro Toxicol Appl Pharmacol 233 203-210

[7] Seidowsky A(2010)Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5 J Endocrinol 205 97-106

[8] Nseir S(2010)Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice Diabetologia 53 1472-1481

[9] Houdret N(2008)Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP Diabetes 57 306-314

[10] Fourrier F(2003)Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysis Arch Intern Med 163 2594-2602