Citridones, New Potentiators of Antifungal Miconazole Activity, Produced by Penicillium sp. FKI-1938II. Structure Elucidation

被引：0
作者：
Takashi Fukuda
Hiroshi Tomoda
Satoshi Ōmura
机构：
[1] School of Pharmaceutical Sciences,
[2] Kitasato University,undefined
[3] Kitasato Institute for Life Sciences & Graduate School of Infection Control Sciences,undefined
[4] Kitasato University,undefined
[5] The Kitasato Institute,undefined
来源：
The Journal of Antibiotics | 2005年 / 58卷
关键词：
citridones; phenylfuropyridone; anti-infective; azole potentiator;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The structures of citridones A, B, B′ and C, new potentiators of miconazole activity against Candida albicans produced by Penicillium sp. FKI-1938, were elucidated by various spectroscopic analyses including UV, NMR, and MS and degradation experiments. Although citridones B and B′ were isolated as a mixture, each structure was also elucidated, indicating that they exist in equilibrium of hemiacetal epimerization. Citridones A, B and B′ have a similar phenylfuropyridone moiety.
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页码：315 / 321
页数：6
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