Systemic administration of orexin A ameliorates established experimental autoimmune encephalomyelitis by diminishing neuroinflammation

[1] Tsujino N(2009)Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system Pharmacol Rev 61 162-176

[2] Sakurai T(2017)Orexin/Hypocretin signaling Curr Top Behav Neurosci 33 17-50

[3] Kukkonen JP(2017)Orexin research: patent news from 2016 Expert Opin Ther Pat 27 1123-1133

[4] Boss C(2010)The effect of orexin-A on the pathological mechanism in the rat focal cerebral ischemia Neurosci Res 68 154-157

[5] Roch C(2018)Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-a Biochim Biophys Acta Mol basis Dis 1864 3618-3628

[6] Kitamura E(2013)Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation Stroke 44 764-770

[7] Hamada J(2015)Role of orexin A signaling in dietary palmitic acid-activated microglial cells Neurosci Lett 606 140-144

[8] Kanazawa N(2011)Effect of orexin-A on post-ischemic glucose intolerance and neuronal damage J Pharmacol Sci 115 155-163

[9] Yonekura J(2011)Neuroprotective effect of orexin-A is mediated by an increase of hypoxia-inducible factor-1 activity in rat Anesthesiology 114 340-354

[10] Masuda R(2014)Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling J Mol Neurosci 52 48-55

[1] Tsujino N(2009)Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system Pharmacol Rev 61 162-176

[2] Sakurai T(2017)Orexin/Hypocretin signaling Curr Top Behav Neurosci 33 17-50

[3] Kukkonen JP(2017)Orexin research: patent news from 2016 Expert Opin Ther Pat 27 1123-1133

[4] Boss C(2010)The effect of orexin-A on the pathological mechanism in the rat focal cerebral ischemia Neurosci Res 68 154-157

[5] Roch C(2018)Ectopic expression of OX1R in ulcerative colitis mediates anti-inflammatory effect of orexin-a Biochim Biophys Acta Mol basis Dis 1864 3618-3628

[6] Kitamura E(2013)Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation Stroke 44 764-770

[7] Hamada J(2015)Role of orexin A signaling in dietary palmitic acid-activated microglial cells Neurosci Lett 606 140-144

[8] Kanazawa N(2011)Effect of orexin-A on post-ischemic glucose intolerance and neuronal damage J Pharmacol Sci 115 155-163

[9] Yonekura J(2011)Neuroprotective effect of orexin-A is mediated by an increase of hypoxia-inducible factor-1 activity in rat Anesthesiology 114 340-354

[10] Masuda R(2014)Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling J Mol Neurosci 52 48-55