High-resolution dynamic mapping of histone-DNA interactions in a nucleosome

被引：0
|
作者：
Michael A Hall
Alla Shundrovsky
Lu Bai
Robert M Fulbright
John T Lis
Michelle D Wang
机构：
[1] Cornell University,Department of Physics—Laboratory of Atomic and Solid State Physics
[2] Cornell University,Department of Molecular Biology and Genetics
[3] Howard Hughes Medical Institute,undefined
[4] Cornell University,undefined
[5] Present addresses: Department of Mechanical Engineering,undefined
[6] Yale University,undefined
[7] New Haven,undefined
[8] Connecticut 06511,undefined
[9] USA (A.S.); Rockefeller University,undefined
[10] 1230 York Avenue,undefined
[11] New York,undefined
[12] New York 10065,undefined
[13] USA (L.B.).,undefined
来源：
Nature Structural & Molecular Biology | 2009年 / 16卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
DNA packaging into nucleosomes presents a barrier to many motor proteins, including the transcriptional machinery. By unzipping DNA in single nucleosomes, a detailed map at near base pair resolution of histone-DNA interactions is now provided, suggesting that interaction with the two DNA strands is decoupled and that unraveling past the dyad axis of the nucleosome, as might occur when a motor protein passes through, is sufficient to displace histones.
引用
收藏
页码：124 / 129
页数：5
相关论文
共 50 条
  • [31] High-resolution genome-wide mapping of histone modifications
    Roh, TY
    Ngau, WC
    Cui, KR
    Landsman, D
    Zhao, KJ
    NATURE BIOTECHNOLOGY, 2004, 22 (08) : 1013 - 1016
  • [32] High-resolution nucleosome mapping reveals transcription-dependent promoter packaging
    Weiner, Assaf
    Hughes, Amanda
    Yassour, Moran
    Rando, Oliver J.
    Friedman, Nir
    GENOME RESEARCH, 2010, 20 (01) : 90 - 100
  • [33] Functionally relevant histone-DNA interactions extend beyond the classically defined nucleosome core region (vol 273, pg 21352, 1998)
    Thiriet, C
    Hayes, JJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (27) : 19507 - 19507
  • [34] HISTONE-DNA INTERACTIONS IN THE CHROMATIN OF PROCYCLIC TRYPANOSOMA-BRUCEI-BRUCEI
    BENDER, K
    BETSCHART, B
    HECKER, H
    PARASITOLOGY RESEARCH, 1992, 78 (06) : 495 - 500
  • [35] The histone fold subunits of Drosophila CHRAC facilitate nucleosome sliding through dynamic DNA interactions
    Hartlepp, KF
    Fernández-Tornero, C
    Eberharter, A
    Grüne, T
    Müller, CW
    Becker, PB
    MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (22) : 9886 - 9896
  • [36] EFFECTS OF DNA-SEQUENCE AND HISTONE-HISTONE INTERACTIONS ON NUCLEOSOME PLACEMENT
    SHRADER, TE
    CROTHERS, DM
    JOURNAL OF MOLECULAR BIOLOGY, 1990, 216 (01) : 69 - 84
  • [37] Understanding histone-DNA interactions in the common bean (Phaseolus vulgaris L.)
    Venu (Kal) Kalavacharla
    Epigenetics & Chromatin, 6 (Suppl 1)
  • [38] High-resolution genome-wide mapping of histone modification by GMAT
    Roh, TY
    Cuddapah, S
    Zhao, KJ
    FASEB JOURNAL, 2005, 19 (04): : A18 - A18
  • [39] High-resolution nucleosome mapping of targeted regions using BAC-based enrichment
    Yigit, Erbay
    Zhang, Quanwei
    Xi, Liqun
    Grilley, Dan
    Widom, Jonathan
    Wang, Ji-Ping
    Rao, Anjana
    Pipkin, Matthew E.
    NUCLEIC ACIDS RESEARCH, 2013, 41 (07)
  • [40] Effects of Psoralen on Histone-DNA Interactions Studied by Using Atomic Force Microscopy
    Zhang, Yingqi
    Zhang, Xiaonong
    Zhang, Wei
    Zhang, Wenke
    MACROMOLECULAR RAPID COMMUNICATIONS, 2020, 41 (24)
12345