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Two New Phenolics from Danshen Injection with Antioxidant Activity
被引：0
作者：
Jing Liu
Yang Liu
Zhong Dai
Gang-Li Wang
Shuang-Cheng Ma
机构：
[1] National Institutes for Food and Drug Control,
来源：
Chemistry of Natural Compounds
|
2018年
/
54卷
关键词：
phenolics;
Danshen injection;
antioxidant activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Danshen Injection (lyophilized powder) is an important clinical preparation with therapeutic effects for cardiovascular diseases in China. Phenolics are considered to be the active ingredients. To investigate the chemical constituents of the injection and assay their antioxidant activities, several column chromatographies were applied to purify and isolate the main chemical constituents of the injection. As a result, two novel phenolic compounds, salvialdehyde acid (1) and glycerol monosalvialdehyde acid ester (2), were isolated. Free radical scavenging activity screening by DPPH· and ABTS·+ methods in vitro indicated compound 1 possessed moderate antioxidant activity.
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页码：1076 / 1080
页数：4
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