Neurofilament light chains (NFL) as prognostic biomarker in the diagnostics of multiple sclerosis

被引：0
|
作者：
Oremek, G. M. [1 ]
Passek, K. [1 ]
Braun, M. [2 ]
Droege, J. [2 ]
Ohlendorf, D. [2 ]
机构：
[1] Goethe Univ Frankfurt, Inst Arbeitsmed Sozialmed & Umweltmed, Abt Lab Diagnost, Theodor Stern Kai 7,Haus 9B, D-60590 Frankfurt, Germany
[2] Goethe Univ Frankfurt, Inst Arbeitsmed Sozialmed & Umweltmed, Frankfurt, Germany
来源：
ZENTRALBLATT FUR ARBEITSMEDIZIN ARBEITSSCHUTZ UND ERGONOMIE | 2022年 / 72卷 / 03期
关键词：
Neurofilament light chains; Multiple sclerosis; Immune system; Magnetic resonance imaging; Cerebrospinal fluid diagnostics; CEREBROSPINAL VENOUS INSUFFICIENCY; HEPATITIS-B VACCINATION; EPSTEIN-BARR-VIRUS; RISK; METAANALYSIS; SMOKING;
D O I：
10.1007/s40664-022-00457-x
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This overview of the biomarker neurofilament light chains (NFL) is published as part of the "Biomarker" series of the Central Journal for Occupational Medicine, Occupational Safety and Ergonomics. The NFL is a serum marker used in the diagnostics of multiple sclerosis. The NFL is suitable as a marker for treatment, progression and recurrence monitoring of multiple sclerosis. Here it shows a high sensitivity and specificity.
引用
收藏
页码：129 / 132
页数：4
相关论文
共 50 条
  • [1] Neurofilament light as a prognostic marker in multiple sclerosis
    Salzer, Jonatan
    Svenningsson, Anders
    Sundstrom, Peter
    MULTIPLE SCLEROSIS JOURNAL, 2010, 16 (03) : 287 - 292
  • [2] NEUROFILAMENT LIGHT CHAIN AS A BIOMARKER FOR DIAGNOSIS OF MULTIPLE SCLEROSIS
    Kouchaki, Ebrahim
    Dashti, Fatemeh
    Mirazimi, Seyed Mohammad Ali
    Alirezaei, Zahra
    Jafari, Seyed Hamed
    Hamblin, Michael R.
    Mirzaei, Hamed
    EXCLI JOURNAL, 2021, 20 : 1308 - 1325
  • [3] Serum neurofilament level as a biomarker in multiple sclerosis
    Jabbar, Huda Qate'a
    Hassoun, Hayder K.
    Allebban, Zuhair
    NEUROLOGY ASIA, 2024, 29 (01) : 183 - 191
  • [4] The potential of serum neurofilament as biomarker for multiple sclerosis
    Bittner, Stefan
    Oh, Jiwon
    Havrdova, Eva Kubala
    Tintore, Mar
    Zipp, Frauke
    BRAIN, 2021, 144 : 2954 - 2963
  • [5] Serum levels of neurofilament light chains in pediatric multiple sclerosis: a systematic review and meta-analysis
    Niculae, Alexandru-Stefan
    Niculae, Lucia-Elena
    Vacaras, Cristiana
    Vacaras, Vitalie
    JOURNAL OF NEUROLOGY, 2023, 270 (10) : 4753 - 4762
  • [6] Serum levels of neurofilament light chains in pediatric multiple sclerosis: a systematic review and meta-analysis
    Alexandru-Ştefan Niculae
    Lucia-Elena Niculae
    Cristiana Văcăraş
    Vitalie Văcăraş
    Journal of Neurology, 2023, 270 : 4753 - 4762
  • [7] Prognostic value of free light chains lambda and kappa in early multiple sclerosis
    Voortman, Margarete M.
    Stojakovic, Tatjana
    Pirpamer, Lukas
    Jehna, Margit
    Langkammer, Christian
    Scharnagl, Hubert
    Reindl, Markus
    Ropele, Stefan
    Seifert-Held, Thomas
    Archelos, Juan-Jose
    Fuchs, Siegrid
    Enzinger, Christian
    Fazekas, Franz
    Khalil, Michael
    MULTIPLE SCLEROSIS JOURNAL, 2017, 23 (11) : 1496 - 1505
  • [8] Serum neurofilament light is a sensitive biomarker that reflects grey matter volume in Japanese patients with multiple sclerosis
    Fujimori, Juichi
    Nakashima, Ichiro
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2021, 427
  • [9] The Evolution of Neurofilament Light Chain in Multiple Sclerosis
    Ferreira-Atuesta, Carolina
    Reyes, Saul
    Giovanonni, Gavin
    Gnanapavan, Sharmilee
    FRONTIERS IN NEUROSCIENCE, 2021, 15
  • [10] Kynurenines and Neurofilament Light Chain in Multiple Sclerosis
    Pukoli, Daniel
    Polyak, Helga
    Rajda, Cecilia
    Vecsei, Laszlo
    FRONTIERS IN NEUROSCIENCE, 2021, 15
12345