Tumorigenesis: Twist1 links EMT to self-renewal

被引：0

作者：

Alberto Martin

Amparo Cano

机构：

[1] Facultad de Medicina,Alberto Martin and Amparo Cano are in the Departamento de Bioquímica

[2] Universidad Autónoma de Madrid,undefined

[3] IdiPAZ,undefined

[4] Arzobispo Morcillo,undefined

[5] 2,undefined

[6] 28029 Madrid,undefined

[7] Spain and the Instituto de Investigaciones Biomédicas “Alberto Sols” Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid,undefined

[8] Arzobispo Morcillo,undefined

[9] 2,undefined

[10] 28029 Madrid,undefined

[11] Spain.,undefined

来源：

Nature Cell Biology | 2010年 / 12卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The epithelial–mesenchymal transition (EMT) occurs in pre-metastatic cancer cells and is also associated with the acquisition of stem-cell-like characteristics. A molecular link between EMT and stemness now emerges with the finding that Bmi1, a polycomb protein that promotes self-renewal of certain stem-cell populations, is a direct transcriptional target of the EMT inducer, Twist1.

引用

页码：924 / 925

页数：1

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