Ribosome-dependent activation of stringent control

被引：0
|
作者：
Alan Brown
Israel S. Fernández
Yuliya Gordiyenko
V. Ramakrishnan
机构：
[1] MRC Laboratory of Molecular Biology,
[2] †Present address: Department of Biochemistry and Molecular Biophysics,undefined
[3] Columbia University,undefined
[4] New York,undefined
[5] New York 10032,undefined
[6] USA.,undefined
来源：
Nature | 2016年 / 534卷
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摘要：
The structure of a bacterial ribosome–RelA complex reveals that RelA, a protein recruited to the ribosome in the case of scarce amino acids, binds in a different location to translation factors, and that this binding event suppresses auto-inhibition to activate synthesis of the (p)ppGpp secondary messenger, thus initiating stringent control.
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页码：277 / 280
页数：3
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