Evaluation of FSH, LH and testosterone levels in different subgroups of infertile males

被引:53
作者
Babu S.R. [1 ]
Sadhnani M.D. [1 ]
Swarna M. [1 ]
Padmavathi P. [1 ]
Reddy P.P. [1 ,2 ]
机构
[1] Inst. Genet./Hosp. Genet. Dis., Osmania University, Begumpet, Hyderabad
[2] Inst. Genet./Hosp. Genet. Dis., Begumpet
关键词
FSH; Hypospermatogenesis; LH; Male infertility; Sertoli - cell only syndrome; Spermatid arrest; Testosterone; Varicocele;
D O I
10.1007/BF02872388
中图分类号
学科分类号
摘要
Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often associated with altered serum gonadotropins and testosterone. FSH, LH and testosterone levels were estimated in 96 infertile men of whom 35 were azoospermic, 35 were oligozoospermic, 11 were with varicocele and 15 were with histopathological abnormalities like hypospermatogenesis, spermatid arrest and sertoli-cell only syndrome. Results showed statistically significant (p< 0.05) increase in the mean FSH and LH levels in all the infertile males studied when compared with the fertile controls (n=35). However, there is no significant difference in the mean levels of testosterone between the infertile and fertile men.
引用
收藏
页码:45 / 49
页数:4
相关论文
共 24 条
[1]  
De Krester D.M., Endocrinology of Male Infertility, Brit. Med. Bullet., 35, 2, pp. 187-192, (1979)
[2]  
O'Donnel L., Mc Lachlan R.I., Wreford N.G., Robertson D.M., Testosterone promotes the conversion of round spermatids between stages vii and viii of the rat spermatogenic cycle, Endocrinology, 135, 4, pp. 2608-2614, (1994)
[3]  
Weinbauer G.F., Nieschlag E., Gonadotropin control of testicular germ cell development, Adv. Exp. Med. Biol., 317, pp. 55-65, (1995)
[4]  
Bergmann M., Behre H., Nieschlag E., Serum FSH and testicular morphology in male infertility, Clin. Endocrinol., 40, pp. 133-136, (1994)
[5]  
Gnessi L., Fabbri A., Spera G., Gonadal peptides as mediators of development and functional control of the testis. An integrated system with hormones and local environment, Endocri. Rev., 18, (1997)
[6]  
Edition, (1992)
[7]  
Zabul J., Mierzejewski W., Rogoza A., Usefulness of examining gonadotropin hormones and testosterone in men with abnormal semen, Ginekol-pol., 65, 2, pp. 71-74, (1994)
[8]  
De Kretser D.M., Clin. Obstet. Gynaecol., 1, pp. 409-427, (1974)
[9]  
Sulthan C., Craste-De-Paulet B., Audran F., Iqbal Y., Ville C., Hormonal evaluation in male infertility, Ann. Biol. Clin. Paris, 43, 1, pp. 63-66, (1985)
[10]  
Weinbauer G.F., Nieschlag E., Gonadotropin control of testicular germ cell development, Adv. Exp. Med. Biol., 317, pp. 55-65, (1995)