In Vivo Induction of Sister Chromatid Exchanges (SCE) in a Tropical Fish, Etroplus suratensis (Bloch)

被引：0

作者：

P. Das

G. John

机构：

[1] Central Marine Fisheries Research Institute,Department of Biotechnology

[2] Ministry of Science and Technology,undefined

来源：

Acta Biologica Hungarica | 1997年 / 48卷 / 2期

关键词：

Fish; mutagens; sister chromatid exchanges; genotoxicity microsomal activation;

D O I：

10.1007/BF03543187

中图分类号：

学科分类号：

摘要：

Sister chromatid exchange (SCE) test was applied to a tropical cultured fish, Etroplus suratensis by exposing to known mutagens. Intramuscular injections of methyl methane sulphonate (MMS) and cyclophosphamide (CP) for an exposure period of 96 h resulted in significant increase in the frequency of SCE in gill tissues. MMS induced dose dependent increase in SCE. The findings revealed that the test species in the present study may be used in mutagenicity assays for screening environmental pollutants.

引用

页码：167 / 172

页数：5

共 26 条

[21] INDUCTION OF SISTER-CHROMATID EXCHANGES, MICRONUCLEI AND GENE-MUTATIONS BY INDIRECTLY ACTING PROMUTAGENS USING HUMAN HEPATOMA-CELLS AS AN ACTIVATION SYSTEM
DARROUDI, F
NATARAJAN, AT
ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 1994, 22 (06): : 445 - 453
[22] A comparative study on the effect of MNU on human lymphocyte cultures in vitro evaluated by O-6-mdG formation, micronuclei and sister chromatid exchanges induction
Stephanou, G
Vlastos, D
Vlachodimitropoulos, D
Demopoulos, NA
CANCER LETTERS, 1996, 109 (1-2) : 109 - 114
[23] Genotoxic effects of styrene-7,8-oxide in human white blood cells:: comet assay in relation to the induction of sister-chromatid exchanges and micronuclei
Laffon, B
Pásaro, E
Méndez, J
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2001, 491 (1-2) : 163 - 172
[24] The role of poly(ADP-ribose) polymerase in the induction of sister chromatid exchanges and micronuclei by mitomycin C in Down's syndrome cells as compared to euploid cells
Caria, H
Quintas, A
Chaveca, T
Rueff, J
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 1997, 377 (02) : 269 - 277
[25] CHROMOSOME-ABERRATIONS (CA), SISTER-CHROMATID EXCHANGES (SCE) AND MITOGEN-INDUCED BLASTOGENESIS IN CULTURED PERIPHERAL LYMPHOCYTES FROM 48 CONTROL INDIVIDUALS SAMPLED 8 TIMES OVER 2 YEARS
ANDERSON, D
FRANCIS, AJ
GODBERT, P
JENKINSON, PC
BUTTERWORTH, KR
MUTATION RESEARCH, 1991, 250 (1-2): : 467 - 476
[26] INDUCTION OF CHROMOSOMAL-ABERRATIONS, SISTER-CHROMATID EXCHANGES AND CELL-CYCLE DELAY IN COW PERIPHERAL-BLOOD LYMPHOCYTES TREATMENT WITH 2 N-NITROSO COMPOUNDS IN-VITRO
SIVIKOVA, K
DIANOVSKY, J
MUTATION RESEARCH, 1993, 290 (02): : 311 - 315

← 1 2 3 →