In Vivo Induction of Sister Chromatid Exchanges (SCE) in a Tropical Fish, Etroplus suratensis (Bloch)

被引：0
|
作者：
P. Das
G. John
机构：
[1] Central Marine Fisheries Research Institute,Department of Biotechnology
[2] Ministry of Science and Technology,undefined
来源：
Acta Biologica Hungarica | 1997年 / 48卷 / 2期
关键词：
Fish; mutagens; sister chromatid exchanges; genotoxicity microsomal activation;
D O I：
10.1007/BF03543187
中图分类号：
学科分类号：
摘要：
Sister chromatid exchange (SCE) test was applied to a tropical cultured fish, Etroplus suratensis by exposing to known mutagens. Intramuscular injections of methyl methane sulphonate (MMS) and cyclophosphamide (CP) for an exposure period of 96 h resulted in significant increase in the frequency of SCE in gill tissues. MMS induced dose dependent increase in SCE. The findings revealed that the test species in the present study may be used in mutagenicity assays for screening environmental pollutants.
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页码：167 / 172
页数：5
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