Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective

[1] Weitzman MD(2005)Functions of the adenovirus E4 proteins and their impact on viral vectors Front Biosci 10 1106-1117

[2] Tomko RP(1997)HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses Proc Natl Acad Sci U S A 94 3352-3356

[3] Xu R(2009)From the first to the third generation adenoviral vector: what parameters are governing the production yield? Biotechnol Adv 27 133-144

[4] Philipson L(2019)Viral vector manufacturing: how to address current and future demands Cell Gene Ther Insights 5 949-970

[5] Dormond E(2016)ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC (2016) Eur Heart J 37 2129-2200

[6] Perrier M(2018)Design of a Phase 3 trial of intracoronary administration of human adenovirus 5 encoding human adenylyl cyclase type 6 (RT-100) gene transfer in patients with heart failure with reduced left ventricular ejection fraction: The FLOURISH Clinical Trial Am Heart J 201 111-116

[7] Kamen A(2016)Understanding heart failure with preserved ejection fraction: where are we today? Neth Heart J 24 227-236

[8] Masri F(2016)Relaxin-2 improves diastolic function of pressure-overloaded rats via phospholamban by activating Akt Int J Cardiol 218 305-311

[9] Cheeseman E(2018)ESC/EACTS Guidelines on myocardial revascularization (2019 Eur Heart J 40 87-165

[10] Ansorge S(2015)ESC/ERS (2016) Guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) Eur Heart J 37 67-119

[1] Weitzman MD(2005)Functions of the adenovirus E4 proteins and their impact on viral vectors Front Biosci 10 1106-1117

[2] Tomko RP(1997)HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses Proc Natl Acad Sci U S A 94 3352-3356

[3] Xu R(2009)From the first to the third generation adenoviral vector: what parameters are governing the production yield? Biotechnol Adv 27 133-144

[4] Philipson L(2019)Viral vector manufacturing: how to address current and future demands Cell Gene Ther Insights 5 949-970

[5] Dormond E(2016)ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure Association (HFA) of the ESC (2016) Eur Heart J 37 2129-2200

[6] Perrier M(2018)Design of a Phase 3 trial of intracoronary administration of human adenovirus 5 encoding human adenylyl cyclase type 6 (RT-100) gene transfer in patients with heart failure with reduced left ventricular ejection fraction: The FLOURISH Clinical Trial Am Heart J 201 111-116

[7] Kamen A(2016)Understanding heart failure with preserved ejection fraction: where are we today? Neth Heart J 24 227-236

[8] Masri F(2016)Relaxin-2 improves diastolic function of pressure-overloaded rats via phospholamban by activating Akt Int J Cardiol 218 305-311

[9] Cheeseman E(2018)ESC/EACTS Guidelines on myocardial revascularization (2019 Eur Heart J 40 87-165

[10] Ansorge S(2015)ESC/ERS (2016) Guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) Eur Heart J 37 67-119