Recent Advances in 3D Bioprinted Tumor Microenvironment

被引:0
作者
Jinseung Bae
Seogkyu Han
Sungsu Park
机构
[1] Sungkyunkwan University,School of Mechanical Engineering
来源
BioChip Journal | 2020年 / 14卷
关键词
Tumors; 3D Bioprinting; Microenvironment; Metastasis; Method;
D O I
暂无
中图分类号
学科分类号
摘要
Tumors in vivo exist in a microenvironment, so-called tumor microenvironment (TME), which includes peripheral blood vessels, immune cells, fibroblasts, signalling molecules and extracellular matrix. In recent years, considerable efforts have been focused on developing bioprinting methods because 3D bioprinting can better recapitulate TMEs by accurately printing different types of TME cells in spatially localised regions. In this review, we first introduce TME and 3D bioprinting methods and later discuss bioprinted TMEs as tumor equivalents for understanding tumor biology as well as testing drug efficacy.
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页码:137 / 147
页数:10
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