G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not

被引:0
|
作者
Xiao-Ju Ni
Olivier Delelis
Charlotte Charpentier
Alexandre Storto
Gilles Collin
Florence Damond
Diane Descamps
Jean-François Mouscadet
机构
[1] LBPA,School of Life Science
[2] CNRS,Laboratoire de Virologie, AP
[3] Ecole Normale Supérieure de Cachan,HP Groupe Hospitalier Bichat
[4] East China Normal University,Claude Bernard
[5] HUPNVS,undefined
[6] Université Paris-Diderot,undefined
[7] Sorbonne Paris Cité,undefined
来源
Retrovirology | / 8卷
关键词
HIV-2; integrase; raltegravir; resistance; mutation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 4 条
  • [1] G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not
    Ni, Xiao-Ju
    Delelis, Olivier
    Charpentier, Charlotte
    Storto, Alexandre
    Collin, Gilles
    Damond, Florence
    Descamps, Diane
    Mouscadet, Jean-Francois
    RETROVIROLOGY, 2011, 8
  • [2] Phenotypic susceptibility of HIV-2 to raltegravir: integrase mutations Q148R and N155H confer raltegravir resistance
    Smith, Robert A.
    Raugi, Dana N.
    Kiviat, Nancy B.
    Hawes, Stephen E.
    Mullins, James I.
    Sow, Papa S.
    Gottlieb, Geoffrey S.
    AIDS, 2011, 25 (18) : 2235 - 2241
  • [3] The G140S mutation in HIV integrases from raltegravir-resistant patients rescues catalytic defect due to the resistance Q148H mutation
    Delelis, Olivier
    Malet, Isabelle
    Na, Li
    Tchertanov, Luba
    Calvez, Vincent
    Marcelin, Anne-Genevieve
    Subra, Frederic
    Deprez, Eric
    Mouscadet, Jean-Franois
    NUCLEIC ACIDS RESEARCH, 2009, 37 (04) : 1193 - 1201
  • [4] Drug Susceptibility and Viral Fitness of HIV-1 with Integrase Strand Transfer Inhibitor Resistance Substitution Q148R or N155H in Combination with Nucleoside/Nucleotide Reverse Transcriptase Inhibitor Resistance Substitutions
    Andreatta, Kristen N.
    Miller, Michael D.
    White, Kirsten L.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2016, 60 (02) : 757 - 765