A survey on awareness of genetic counseling for non-invasive prenatal testing: the first year experience in Japan

被引：0

作者：

Junko Yotsumoto

Akihiko Sekizawa

Nobuhiro Suzumori

Takahiro Yamada

Osamu Samura

Miyuki Nishiyama

Kiyonori Miura

Hideaki Sawai

Jun Murotsuki

Michihiro Kitagawa

Yoshimasa Kamei

Hideaki Masuzaki

Fumiki Hirahara

Toshiaki Endo

Akimune Fukushima

Akira Namba

Hisao Osada

Yasuyo Kasai

Atsushi Watanabe

Yukiko Katagiri

Naoki Takeshita

Masaki Ogawa

Takashi Okai

Shunichiro Izumi

Haruka Hamanoue

Mayuko Inuzuka

Kazufumi Haino

Naoki Hamajima

Haruki Nishizawa

Yoko Okamoto

Hiroaki Nakamura

Takeshi Kanegawa

Jun Yoshimatsu

Shinya Tairaku

Katsuhiko Naruse

Hisashi Masuyama

Maki Hyodo

Takashi Kaji

Kazuhisa Maeda

Keiichi Matsubara

Masanobu Ogawa

Toshiyuki Yoshizato

Takashi Ohba

Yukie Kawano

Haruhiko Sago

机构：

[1] Faculty of Core Research,Natural Science Division

[2] Ochanomizu University,Department of Obstetrics and Gynecology

[3] Showa University School of Medicine,Division of Clinical and Molecular Genetics, Department of Obstetrics and Gynecology

[4] Nagoya City University Graduate School of Medical Sciences,Department of Obstetrics and Gynecology

[5] Hokkaido University Graduate School of Medicine,Department of Obstetrics and Gynecology

[6] The Jikei University School of Medicine,Department of Obstetrics and Gynecology

[7] Center of Maternal-Fetal,Department of Obstetrics and Gynecology

[8] Neonatal and Reproductive Medicine,Department of Maternal and Fetal Medicine

[9] National Center for Child Health and Development,Department of Obstetrics and Gynecology

[10] Nagasaki University Graduate School of Biomedical Sciences,Department of Obstetrics and Gynecology

[11] Hyogo College of Medicine,Department of Obstetrics and Gynecology

[12] Tohoku University Graduate School of Medicine,Department of Obstetrics and Gynecology

[13] Miyagi-Children's Hospital,Department of Clinical Genetics

[14] Sanno Hospital,Department of Obstetrics and Gynecology

[15] Saitama Medical University Hospital,Department of Obstetrics and Gynecology

[16] Yokohama City University Graduate School of Medicine,Division of Clinical Genetics

[17] Sapporo Medical University School of Medicine,Department of Obstetrics and Gynecology

[18] Iwate Medical University School of Medicine,Department of Obstetrics and Gynecology

[19] Chiba University Graduate School of Medicine,Department of Obstetrics and Gynecology

[20] Japanese Red Cross Medical Center,Department of Clinical Genetics

[21] Nippon Medical School Hospital,Department of Obstetrics and Gynecology

[22] Toho University Omori Medical Center,Department of Obstetrics

[23] Perinatal Medical Center,Department of Obstetrics

[24] Tokyo Women’s Medical University Hospital,Department of Obstetrics and Gynecology

[25] Maternal and Child Health Center,Department of Perinatology and Gynecology

[26] Aiiku Hospital,Department of Obstetrics and Gynecology

[27] Tokai University School of Medicine,Department of Obstetrics and Gynecology

[28] Niigata University Medical and Dental Hospital,Department of Obstetrics and Gynecology

[29] Nagoya City West Medical Center,Department of Obstetrics and Gynecology

[30] Fujita Health University,Department of Obstetrics and Gynecology

[31] Osaka Medical Center and Research Institute for Maternal and Child Health,Department of Obstetrics and Gynecology

[32] Osaka City General Hospital,undefined

[33] Osaka University Faculty of Medicine,undefined

[34] National Cerebral and Cardiovascular Center,undefined

[35] Kobe University Graduate School of Medicine,undefined

[36] Nara Medical University,undefined

[37] Okayama University Graduate School of Medicine,undefined

[38] Hiroshima University Graduate School of Medicine,undefined

[39] The University of Tokushima Faculty of Medicine,undefined

[40] Shikoku Medical Center for Children and Adults,undefined

[41] Ehime University School of Medicine,undefined

[42] Clinical Research Institute,undefined

[43] National Hospital Organization Kyushu Medical Center,undefined

[44] Center for Maternal,undefined

[45] Fetal and Neonatal Medicine,undefined

[46] Fukuoka University Hospital,undefined

[47] Kumamoto University,undefined

[48] Genetic Counselling Office,undefined

[49] Oita University Hospital,undefined

来源：

Journal of Human Genetics | 2016年 / 61卷

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摘要：

The purpose of this study is to summarize the results from a survey on awareness of genetic counseling for pregnant women who wish to receive non-invasive prenatal testing (NIPT) in Japan. As a component of a clinical study by the Japan NIPT Consortium, genetic counseling was conducted for women who wished to receive NIPT, and a questionnaire concerning both NIPT and genetic counseling was given twice: once after pre-test counseling and again when test results were reported. The responses of 7292 women were analyzed. They expressed high satisfaction with the genetic counseling system of the NIPT Consortium (94%). The number of respondents who indicated that genetic counseling is necessary for NIPT increased over time. Furthermore, they highly valued genetic counseling provided by skilled clinicians, such as clinical geneticists or genetic counselors. The vast majority (90%) responded that there was sufficient opportunity to consider the test ahead of time. Meanwhile, women who received positive test results had a poor opinion and expressed a low-degree satisfaction. We confirmed that the pre-test genetic counseling that we conducted creates an opportunity for pregnant women to sufficiently consider prenatal testing, promotes its understanding and has possibilities to effectively facilitate informed decision making after adequate consideration. A more careful and thorough approach is considered to be necessary for women who received positive test results.

引用

页码：995 / 1001

页数：6

共 94 条

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