Planting new targets for antiparasitic drugs

被引:0
作者
Robert G. Ridley
机构
[1] Pharma Research,
[2] Preclinical Infectious Diseases,undefined
来源
Nature Medicine | 1998年 / 4卷
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摘要
An organelle in apicomplexan parasites including those causing malaria and toxoplasmosis may be the site of a plant biosynthetic pathway that could provide new targets for drug discovery and development.
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页码:894 / 895
页数:1
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  • [1] Fichera ME(1997)A plastid organdie as a drug target in apicomplexan parasites Nature 390 407-409
  • [2] Roos DS(1996)Complete gene map of the plastid-like DNA of the malaria parasite J. Mol. Biol. 261 155-172
  • [3] Wilson RJM(1997)A plastid of probable green algal origin in apicomplexan parasites Science 275 1485-1489
  • [4] Köhler S(1998)Evidence for shikimate pathway in apicomplexan parasites Nature 393 801-805
  • [5] Roberts F(1990)The shikimate pathway—a Crit. Rev. Biochem. Mol. Biol. 25 307-383
  • [6] Bentley R(1996) tree with many branches Nature 381 482-304
  • [7] McFadden GI(1997)Plastid in human parasites Exptl. Parasitol. 87 293-512
  • [8] Reith ME(1996)Antimalarial drug discovery and development—an industrial perspective Curr. Opin. Cell Biol. 8 505-305
  • [9] Munholland J(1992)Biogenesis of mitochondrial proteins Annu. Rev. Plant Physiol. Plant Mol. Biol. 43 241-296
  • [10] Lang-Unnasch N(1998)Spatial organisation of enzymes in plant metabolic pathways Mol. Biochem. Parasitol. 91 295-28