Pharmacokinetic Interactions with FelbamateIn Vitro-In Vivo Correlation

被引：0
|
作者：
Paul Glue
Christopher R. Banfield
James L. Perhach
Gary G. Mather
Jagdish K. Racha
Rene H. Levy
机构：
[1] Schering-Plough Research Institute,Clinical Pharmacology
[2] Wallace Laboratories,Department of Pharmacology
[3] University of Washington,undefined
来源：
Clinical Pharmacokinetics | 1997年 / 33卷
关键词：
Carbamazepine; Valproic Acid; Lamotrigine; Vigabatrin; Oxcarbazepine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This article provides an analysis of the degree of agreement between in vivo interaction studies performed in patients with epilepsy and healthy individuals, and in vitro studies which identified the cytochromes P450 (CYP) inhibited by felbamate and those involved in its metabolism.
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页码：214 / 224
页数：10
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