Inflammation and lipid-lowering treatment

被引：1
作者：
Ballantyne C.M. [1 ]
Abe Y. [1 ]
机构：
[1] Department of Medicine, Baylor College of Medicine, 6565 Fannin, MS A-601, Houston
来源：
Current Cardiology Reports | 1999年 / 1卷 / 3期
关键词：
Atorvastatin; Cell Adhesion Molecule; Arterioscler Thromb Vasc Biol; Endothelial Cell Adhesion Molecule; Human Vascular Endothelial Cell;
D O I：
10.1007/s11886-999-0031-y
中图分类号：
学科分类号：
摘要：
Leukocytes play a critical role in both the initial steps of atherogenesis and the late events of plaque instability and thrombosis. Leukocyte-endothelial cell adhesion molecules (CAMs) modulate the interaction between circulating leukocytes and the vessel wall. Levels of soluble CAMs are increased in patients with dyslipidemia or other risk factors, and levels can be reduced by lipid-modifying therapy. Novel markers of inflammation and atherosclerosis may be useful to identify high-risk individuals and to assess the efficacy of antiatherosclerotic therapy. Copyright © 1999 by Current Science Inc.
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页码：251 / 255
页数：4
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