Mediastinal B-cell lymphoma, a lymphoma type with several characteristics unique among diffuse large B-cell lymphomas

被引:0
作者
Thomas F. E. Barth
Frank Leithäuser
Peter Möller
机构
[1] Institute of Pathology,
[2] University of Ulm,undefined
[3] Ulm,undefined
[4] Germany,undefined
[5] e-mail: peter.moeller@medizin.uni-ulm.de,undefined
[6] Tel.: +49-(0)731-5023320,undefined
[7] Fax: +49-(0)731-5023884,undefined
关键词
Keywords Mediastinal B-cell lymphoma; Histomorphology; Immunology; Genetics;
D O I
10.1007/PL00022789
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摘要
Mediastinal B-cell lymphoma is a locally highly aggressive tumor with a rather unique pattern of clinical, morphologic, imunologic, and genetic features distinct from other diffuse large B-cell lymphomas. Characterization of this disease has been bampered by the relatively low incidence of this lymphoma type. Although recent studies on larger numbers of cases have allowed new insights into biology and clinics of this lymphoma type, the histogenesis of mediastinal B-cell lymphoma is not yet fully understood. This review will list morphologic, immunlogic, and genetic properties of mediastinal B-cell lymphoma and discuss recent data regarding the biology of this lymphoma type.
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页码:B49 / B53
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