Inhibition of epidermal growth factor receptor by ferulic acid and 4-vinylguaiacol in human breast cancer cells

[1] Peng YH(2013)Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors J Med Chem 56 3889-3903

[2] Shiao HY(2016)Plant phenolics ferulic acid and p-coumaric acid inhibit colorectal cancer cell proliferation through EGFR down-regulation Asian Pac J Cancer Prev 7 4019-4023

[3] Tu CH(2017)Computational and experimental characterization of patient derived mutations reveal an unusual mode of regulatory spine assembly and drug sensitivity in EGFR Kinase Biochemistry 56 22-32

[4] Liu PM(2014)EGFR inhibition by pentacyclic triterpenes exhibit cell cycle and growth arrest in breast cancer cells Life Sci 95 53-62

[5] Hsu JT(2011)Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells Chem Res Toxicol 24 763-774

[6] Amancha PK(2013)Transitions to catalytically inactive conformations in EGFR kinase Proc Natl Acad Sci USA 110 7270-7275

[7] Wu JS(2007)Ferulic acid: therapeutic potential through its antioxidant property J Clin Biochem Nutr 40 92-100

[8] Coumar MS(2016)Ferulic acid inhibits proliferation and promotes apoptosis via blockage of PI3K/Akt pathway in osteosarcoma cell Am J Transl Res 8 968-980

[9] Chen CH(2015)Ferulic acid exerts anti-angiogenic and anti-tumor activity by targeting fibroblast growth factor receptor 1-mediated angiogenesis Int J Mol 16 24011-24031

[10] Wang SY(2007)Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity Cancer Cell 11 217-227

[1] Peng YH(2013)Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors J Med Chem 56 3889-3903

[2] Shiao HY(2016)Plant phenolics ferulic acid and p-coumaric acid inhibit colorectal cancer cell proliferation through EGFR down-regulation Asian Pac J Cancer Prev 7 4019-4023

[3] Tu CH(2017)Computational and experimental characterization of patient derived mutations reveal an unusual mode of regulatory spine assembly and drug sensitivity in EGFR Kinase Biochemistry 56 22-32

[4] Liu PM(2014)EGFR inhibition by pentacyclic triterpenes exhibit cell cycle and growth arrest in breast cancer cells Life Sci 95 53-62

[5] Hsu JT(2011)Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells Chem Res Toxicol 24 763-774

[6] Amancha PK(2013)Transitions to catalytically inactive conformations in EGFR kinase Proc Natl Acad Sci USA 110 7270-7275

[7] Wu JS(2007)Ferulic acid: therapeutic potential through its antioxidant property J Clin Biochem Nutr 40 92-100

[8] Coumar MS(2016)Ferulic acid inhibits proliferation and promotes apoptosis via blockage of PI3K/Akt pathway in osteosarcoma cell Am J Transl Res 8 968-980

[9] Chen CH(2015)Ferulic acid exerts anti-angiogenic and anti-tumor activity by targeting fibroblast growth factor receptor 1-mediated angiogenesis Int J Mol 16 24011-24031

[10] Wang SY(2007)Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity Cancer Cell 11 217-227