SPINT2 is hypermethylated in both IDH1 mutated and wild-type glioblastomas, and exerts tumor suppression via reduction of c-Met activation

[1] Parsons DW(2008)An integrated genomic analysis of human glioblastoma multiforme Science 321 1807-1812

[2] Jones S(2012)Recent advances in the molecular understanding of glioblastoma J Neuro Oncol 108 11-27

[3] Zhang X(2013)The somatic genomic landscape of glioblastoma Cell 155 462-477

[4] Lin JC(2010)Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma Cancer Cell 17 510-522

[5] Leary RJ(2004)CpG island methylator phenotype in cancer Nat Rev Cancer 4 988-993

[6] Angenendt P(2006)The consensus coding sequences of human breast and colorectal cancers Science 314 268-274

[7] Mankoo P(2009)Recurring mutations found by sequencing an acute myeloid leukemia genome N Engl J Med 361 1058-1066

[8] Carter H(2010)Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas Eur J Endocrinol 163 747-755

[9] Siu IM(2011)IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours J Pathol 224 334-343

[10] Gallia GL(2012)Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping Oncologist 17 72-79

[1] Parsons DW(2008)An integrated genomic analysis of human glioblastoma multiforme Science 321 1807-1812

[2] Jones S(2012)Recent advances in the molecular understanding of glioblastoma J Neuro Oncol 108 11-27

[3] Zhang X(2013)The somatic genomic landscape of glioblastoma Cell 155 462-477

[4] Lin JC(2010)Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma Cancer Cell 17 510-522

[5] Leary RJ(2004)CpG island methylator phenotype in cancer Nat Rev Cancer 4 988-993

[6] Angenendt P(2006)The consensus coding sequences of human breast and colorectal cancers Science 314 268-274

[7] Mankoo P(2009)Recurring mutations found by sequencing an acute myeloid leukemia genome N Engl J Med 361 1058-1066

[8] Carter H(2010)Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas Eur J Endocrinol 163 747-755

[9] Siu IM(2011)IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours J Pathol 224 334-343

[10] Gallia GL(2012)Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping Oncologist 17 72-79