Environmental factors and hormones in the development of rheumatoid arthritis

被引:0
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作者
Deshiré Alpízar-Rodríguez
Axel Finckh
机构
[1] University Hospitals of Geneva,Division of Rheumatology, Department of Internal Medicine Specialties
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关键词
Rheumatoid arthritis; Risk factors; Environmental factors; Hormonal factors; Reproductive factors;
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摘要
The etiopathogenesis of rheumatoid arthritis (RA) is partially understood. Genetic, environmental, and hormonal factors and their interactions are considered to play an important role on disease development. The relative contribution of environmental factors to RA development is probably larger than previously thought. The aim of this review is to appraise robust evidence about the role of environmental and hormonal risk factors for RA. We will discuss inhaled pollutants, nutritional habits, infectious, hormonal, and reproductive factors. As some of these factors are potentially modifiable, understanding their impact on RA development opens new opportunities for potential interventions and disease prevention.
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页码:461 / 468
页数:7
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