Genotype-guided versus traditional clinical dosing of warfarin in patients of Asian ancestry: a randomized controlled trial

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作者
Nicholas L. Syn
Andrea Li-Ann Wong
Soo-Chin Lee
Hock-Luen Teoh
James Wei Luen Yip
Raymond CS Seet
Wee Tiong Yeo
William Kristanto
Ping-Chong Bee
LM Poon
Patrick Marban
Tuck Seng Wu
Michael D. Winther
Liam R. Brunham
Richie Soong
Bee-Choo Tai
Boon-Cher Goh
机构
[1] National University Cancer Institute,Department of Haematology
[2] National University of Singapore,Oncology
[3] National University Health System,Cancer Science Institute of Singapore
[4] National University Heart Centre,Division of Neurology, Department of Medicine
[5] University of Malaya Medical Centre,Department of Cardiology
[6] National University Hospital,Department of Medicine
[7] Genome Institute of Singapore,Department of Pharmacy
[8] Agency for Science,Department of Medicine, Centre for Heart Lung Innovation
[9] Technology and Research,Department of Pathology
[10] Translational Laboratory in Genetic Medicine,Saw Swee Hock School of Public Health
[11] Agency for Science,Department of Pharmacology
[12] Technology and Research,Department of Medicine
[13] University of British Columbia,undefined
[14] Yong Loo Lin School of Medicine,undefined
[15] National University Health System,undefined
[16] National University of Singapore,undefined
[17] Yong Loo Lin School of Medicine,undefined
[18] National University Health System,undefined
[19] Yong Loo Lin School of Medicine,undefined
[20] National University of Singapore,undefined
来源
BMC Medicine | / 16卷
关键词
Pharmacogenetics; Pharmacogenomics; Precision medicine; CYP2C9; Cytochrome P450; VKORC1; Warfarin; Anticoagulants; Anticoagulation; Polymorphism;
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