933 Nitric Oxide and Lipid Peroxidation are Increased and Associated with Decreased Antioxidant Enzyme Activities in Children with Nosocomial Pneumonia

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作者：
D Dmytriiev
O Katilov
K Dmytriieva
机构：
[1] Vinnitsa National Medical University,
来源：
Pediatric Research | 2010年 / 68卷
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摘要：
Background: Nitric oxide (NO), hydroxyl radical (OH*), superoxide anion (O2-) and hydrogen peroxide (H2O2) are free-radicals released in oxidative stress. Superoxide dismutase (SOD), glutathione peroxidase (GSHPx) and catalase (CAT) are antioxidant enzymes, mediating defense against oxidative stress. Excess NO and/or defective antioxidants cause lipid peroxidation, cellular dysfunction and death. Nosocomial pneumonia (NP) the leading cause of death in children.
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页码：466 / 466
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