Sepsis-associated encephalopathy (SAE) is a clinical syndrome that is associated with diffuse brain dysfunction and is secondary to infection in the body. Severity of SAE ranges from mild delirium to deep coma, and mortality reaches almost 70% in severe cases. In this Review, Gofton and Young provide an overview of the epidemiology and clinical presentation of SAE. They discuss current evidence relating to the pathophysiology and prognosis of SAE, and present a diagnostic approach and management strategy for patients with the disease.
机构:
Univ Napoli Federico II, Dipartimento Sci Chirurg Anestesiol Rianimatorie, Naples, ItalyUniv Napoli Federico II, Dipartimento Sci Chirurg Anestesiol Rianimatorie, Naples, Italy
Cotena, Simona
Piazza, Ornella
论文数: 0引用数: 0
h-index: 0
机构:
Univ Salerno, Dipartimento Anestesia & Rianimaz, Salerno, ItalyUniv Napoli Federico II, Dipartimento Sci Chirurg Anestesiol Rianimatorie, Naples, Italy
Piazza, Ornella
TRANSLATIONAL MEDICINE AT UNISA,
2012,
2
: 20
-
27
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Feng, Qing
Ai, Yu-Hang
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Ai, Yu-Hang
Gong, Hua
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Gong, Hua
Wu, Long
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Wu, Long
Ai, Mei-Lin
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Ai, Mei-Lin
Deng, Song-Yun
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Deng, Song-Yun
Huang, Li
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Huang, Li
Peng, Qian-Yi
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
Peng, Qian-Yi
Zhang, Li-Na
论文数: 0引用数: 0
h-index: 0
机构:
Cent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R ChinaCent S Univ, Xiangya Hosp, Dept Intens Care Unit, Changsha 410008, Hunan, Peoples R China
机构:
AP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, FranceAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
Heming, Nicholas
Mazeraud, Aurelien
论文数: 0引用数: 0
h-index: 0
机构:
Inst Pasteur, Human Histopathol & Anim Models, F-75015 Paris, FranceAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
Mazeraud, Aurelien
Verdonk, Franck
论文数: 0引用数: 0
h-index: 0
机构:
Inst Pasteur, Human Histopathol & Anim Models, F-75015 Paris, FranceAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
Verdonk, Franck
Bozza, Fernando A.
论文数: 0引用数: 0
h-index: 0
机构:
Fiocruz MS, Evandro Chagas Natl Inst Infect Dis, Rio De Janeiro, BrazilAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
Bozza, Fernando A.
Chretien, Fabrice
论文数: 0引用数: 0
h-index: 0
机构:
St Anne Hosp, Unit Neuropathol, Paris, FranceAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
Chretien, Fabrice
Sharshar, Tarek
论文数: 0引用数: 0
h-index: 0
机构:
Hop Raymond Poincare, Gen ICU, Garches, FranceAP HP, Hop Raymond Poincare, Reanim Med, 104 Blvd Raymond Poincare, F-92380 Garches, France
机构:
Inst Pasteur, Dept Infect & Epidemiol, Paris, France
Med & Surg Neurointens Care Ctr Hospitalier St An, Paris, France
Univ Paris 05, Paris, FranceInst Pasteur, Dept Infect & Epidemiol, Paris, France
Mazeraud, Aurelien
Bozza, Fernando A.
论文数: 0引用数: 0
h-index: 0
机构:
Fundacao Oswaldo Cruz, Rio De Janeiro, BrazilInst Pasteur, Dept Infect & Epidemiol, Paris, France