Apoptosis and necrosis: Intracellular ATP level as a determinant for cell death modes

被引:0
作者
Yoshihide Tsujimoto
机构
[1] Osaka University Medical School,
[2] Biomedical Research Center,undefined
来源
Cell Death & Differentiation | 1997年 / 4卷
关键词
ATP; necrosis; apoptosis; mitochondria; bcl-2; caspase;
D O I
暂无
中图分类号
学科分类号
摘要
Apoptosis and necrosis are two distinct modes of cell death with respective morphological characteristics. However, apoptosis and some forms of necrosis must share common steps since both modes of cell death can be suppressed by the anti-apoptotic Bcl-2 protein and caspase inhibitors. Intracellular ATP levels have been implicated both in vitro and in vivo as a determinant of the cell's decision to die by apoptosis or necrosis.
引用
收藏
页码:429 / 434
页数:5
相关论文
empty
未找到相关数据