Senescence: back to telomeres

被引:0
作者
Jacqueline J. L. Jacobs
机构
[1] The Netherlands Cancer Institute,
来源
Nature Reviews Molecular Cell Biology | 2013年 / 14卷
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学科分类号
摘要
The demonstration that senescence is caused by both telomere erosion and oncogene-induced accumulation of DNA damage at telomeres.
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页码:196 / 196
相关论文
共 4 条
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[2]  
Fumagalli M(2012) provokes premature cell senescence associated with accumulation of p53 and p16 Nature Cell Biol. 14 355-365
[3]  
Hewitt G(2012)Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation Nature Commun. 3 708-2851
[4]  
Suram A(2012)Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence EMBO J. 31 2839-undefined