A pharmacokinetic interaction between carbamazepine and olanzapine: observations on possible mechanism

被引：0
|
作者：
R. A. Lucas
D. J. Gilfillan
R. F. Bergstrom
机构：
[1] Eli Lilly and Company Limited,
[2] Lilly Research Centre,undefined
[3] Erl Wood Manor,undefined
[4] Sunninghill Road,undefined
[5] Windlesham,undefined
[6] Surrey GU20 6PH,undefined
[7] UK e-mail: LUCAS_RICHARD@LILLY.COM Tel.: +44-1276-853311; Fax: +44-1276-853565,undefined
[8] Lilly Laboratory for Clinical Research,undefined
[9] Wishard Memorial Hospital,undefined
[10] Indianapolis,undefined
[11] Indiana,undefined
[12] USA,undefined
来源：
European Journal of Clinical Pharmacology | 1998年 / 54卷
关键词：
Key words Olanzapine; Carbamazepine; Drug interaction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: Olanzapine is a novel antipsychotic, which is effective against both the positive and negative symptoms of schizophrenia and causes fewer extrapyramidal adverse effects than conventional antipsychotics. The purpose of the present study was to assess the potential for a pharmacokinetic interaction between olanzapine and carbamazepine, since these agents are likely to be used concomitantly in the treatment of manic psychotic disorder.
引用
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页码：639 / 643
页数：4
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