Imaging pain of fibromyalgia

被引：20

作者：

Cook D.B. ^{[1
,2
]}

Stegner A.J.

McLoughlin M.J.

机构：

[1] William S. Middleton Memorial Veterans Hospital, Madison

[2] Department of Kinesiology, University of Wisconsin, Madison

来源：

Current Pain and Headache Reports | 2007年 / 11卷 / 3期

关键词：

Irritable Bowel Syndrome; Chronic Fatigue Syndrome; Irritable Bowel Syndrome Patient; Chronic Pain Patient; Anterior Insula;

D O I：

10.1007/s11916-007-0190-8

中图分类号：

学科分类号：

摘要：

Brain imaging studies have provided objective evidence of abnormal central regulation of pain in fibromyalgia (FM). Resting brain blood flow studies have reported mixed findings for several brain regions, whereas decreased thalamic blood flow has been noted by several investigators. Studies examining the function of the nociceptive system in FM have reported augmented brain responses to both painful and non-painful stimuli that may be influenced by psychologic dispositions such as depressed mood and catastrophizing. Treatment approaches are beginning to demonstrate the potential for brain imaging to improve our understanding of pain-alleviating mechanisms. Data from other chronic conditions suggest that idiopathic pain may be maintained by similar central abnormalities as in FM, whereas chronic pain conditions with a known nociceptive source may not be. Future neuroimaging research in FM is clearly warranted and should continue to improve our understanding of factors involved in pain maintenance and symptom exacerbation. Copyright © 2007 by Current Medicine Group LLC.

引用

页码：190 / 200

页数：10

共 47 条

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