Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health

被引：0
作者：
Iman Halvaei
Julia Litzky
Navid Esfandiari
机构：
[1] Tarbiat Modares University,Department of Anatomical Sciences, Faculty of Medical Sciences
[2] Department of Pediatrics,Department of Obstetrics, Gynecology and Reproductive Sciences
[3] Dartmouth Hitchcock Medical Center,undefined
[4] University of Vermont Medical Center,undefined
[5] Larner College of Medicine,undefined
来源：
Reproductive Biology and Endocrinology | / 18卷
关键词：
Male age; Aging; Pregnancy; Live birth; Sperm;
D O I：
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中图分类号：
学科分类号：
摘要：
Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.
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