Postoperative chemo–endocrine treatment with mitomycin C, tamoxifen, and UFT is effective for patients with premenopausal estrogen receptor–positive stage II breast cancer

被引:0
作者
Keizo Sugimachi
Yoshihiko Maehara
Kohei Akazawa
Yasuo Nomura
Kazuyuki Eida
Michio Ogawa
Eiji Konaga
Noriaki Tanaka
Tetsuya Toge
Kiyohiko Dohi
Shoichihi Noda
Masazumi Maeda
Yasumasa Monden
机构
[1] Kyushu University,Department of Surgery II, Faculty of Medicine
[2] Kyushu University,Department of Medical Informatics, Faculty of Medicine
[3] National Kyushu Cancer Center Hospital,Department of Surgery II
[4] Nagasaki Red Cross Hospital,Department of Surgery I
[5] Kumamoto University Medical School,The Department of Surgery, Research Institute for Nuclear Medicine and Biology
[6] National Iwakuni Hospital,Department of Surgery II
[7] Okayama University Medical School,Department of Surgery II
[8] Hiroshima University,Department of Surgery II, School of Medicine
[9] Hiroshima University School of Medicine,undefined
[10] National Beppu Hospital,undefined
[11] Kagawa Medical University,undefined
[12] The University of Tokushima,undefined
关键词
breast cancer; estrogen receptor; mitomycin C; postoperative chemotherapy; tamoxifen; UFT;
D O I
10.1023/A:1006221425652
中图分类号
学科分类号
摘要
The effectiveness of combining mitomycin C (MMC), tamoxifen (TAM), and 1-(2-tetrahydrofuryl)-5-fluorouracil (tegafur) was evident in patients with estrogen receptor-positive (ER+) breast cancers. UFT, an oral preparation of tegafur and uracil at a molar ratio of 1:4, was reported to have higher antitumor effects than tegafur alone for patients with breast cancer. Therefore, the combined chemotherapy of MMC, TAM and UFT may possibly be effective for breast cancer.
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页码:111 / 122
页数:11
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