Comparison of target coverage and dose to organs at risk between simultaneous integrated-boost whole-field intensity-modulated radiation therapy and junctioned intensity-modulated radiation therapy with a conventional radiotherapy field in treatment of nasopharyngeal carcinoma

被引：7

作者：

Chung J.-B. ^{[1
]}

Lee J.-W. ^{[3
]}

Kim J.-S. ^{[1
]}

Kim I.-A. ^{[1
]}

Lee D.-H. ^{[4
]}

Kim Y.-L. ^{[2
]}

Choi K.-S. ^{[5
]}

Choe B.-Y. ^{[2
]}

Suh T.-S. ^{[2
]}

机构：

[1] Department of Radiation Oncology, Seoul National University, Budang Hospital, Bundang-gu, Seongnam, Gyeonggi-do 463-802

[2] Department of Biomedical Engineering, Earch Institute of Biomedical Engineering, Catholic University of Korea, Seocho-gu, Seoul 137-701

[3] Department of Radiation Oncology, Konkuk University, Konkuk University Hospital, Gwangjin-gu, Seoul 143-729

[4] Department of Radiation Oncology, National Cancer Center, Ilsandong-gu, Goyang, Gyeonggi-do 410-810

[5] Department of Radiation Oncology, Anyang Sam Hospital, Manan-gu, Anyang, Gyeonggi-do 430-849

来源：

Radiological Physics and Technology | 2011年 / 4卷 / 2期

基金：

新加坡国家研究基金会;

关键词：

Intensity-modulated radiation therapy; Junctioned IMRT; Nasopharyngeal carcinoma; Simultaneous integrated-boost whole-field IMRT;

D O I：

10.1007/s12194-011-0119-0

中图分类号：

学科分类号：

摘要：

We have retrospectively investigated 15 nasopharyngeal carcinoma patients treated at our institution between March 2007 and August 2009. We used simultaneous integrated-boost whole field intensity-modulated radiation therapy (SIB WF-IMRT) to treat the entire planning target volume in the head and neck cancer. All of the SIB WF-IMRT plans were replanned by use of the junctioned intensity modulated radiation therapy (J-IMRT) technique for comparison. The effect on target coverage and sparing of organs at risk, including laryngeal sparing in the optimal SIB WF-IMRT plan was compared with that achieved with use of the J-IMRT technique. The mean larynx dose and standard deviation was 25.2 ± 5.8 Gy for SIB WF-IMRT and 19.8 ± 16.8 Gy for J-IMRT. A comparison between SIB WF-IMRT and the J-IMRT technique demonstrated that the larynx dose was increased in SIB WF-IMRT. However, when the strong dose constraint was applied to the larynx and the pseudo-volume was used for a steep dose fall-off immediately outside the target, the SIB WF-IMRT technique would have led to a larynx dose comparable to that achieved with J-IMRT. Therefore, in our current practice we use the SIB WF-IMRT technique, which does not have the problem of setup error at the match line for treatment of nasopharyngeal carcinoma. © 2011 Japanese Society of Radiological Technology and Japan Society of Medical Physics.

引用

页码：180 / 184

页数：4

共 13 条

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