Oral Mycosis Fungoides: A Report of Three Cases and Review of the Literature

被引:0
作者
Molly S. Rosebush
Carl M. Allen
Brent T. Accurso
Robert A. Baiocchi
Kitrina G. Cordell
机构
[1] Louisiana State University,Division of Hematology
[2] Central Ohio Skin & Cancer,undefined
[3] Inc.,undefined
[4] The Ohio State University,undefined
[5] Oral Pathology Consultants,undefined
[6] PLLC,undefined
[7] The Ohio State University College of Medicine,undefined
来源
Head and Neck Pathology | 2019年 / 13卷
关键词
Mycosis fungoides; Sézary syndrome; T cell lymphoma; Oral cavity;
D O I
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中图分类号
学科分类号
摘要
Mycosis fungoides (MF) and Sézary syndrome are clonal T-cell proliferations that exhibit skin homing and represent the majority of cutaneous T-cell lymphomas. Early MF is a diagnostic challenge as both the clinical and microscopic features often mimic benign inflammatory conditions. Oral MF is very rare and has been associated in the past with advanced disease and a poor prognosis. Skin lesions are present for an average of > 6 years before oral involvement occurs. The clinical appearance is highly variable with tongue, palate and gingiva most often affected. We report 3 additional cases of oral MF, including one in which oral lesions are the initial disease presentation. Survival in patients presenting with oral MF is improving and can be attributed to advances in therapy.
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页码:492 / 499
页数:7
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共 184 条
[31]  
Capetanakis JP(2014)Oral mycosis fungoides: report with immune profile Oral Surg Oral Med Oral Pathol Oral Radiol 118 e48-302
[32]  
Crane RM(2016)Mycosis fungoides of the oral cavity: fungating tumor successfully treated with electron beam radiation and maintenance bexarotene Case Rep Dermatol Med 2016 5857935-e331
[33]  
Heydt S(2016)A rare case of mycosis fungoides in the oral cavity and small intestine complicated by perforation Case Rep Dermatol. 8 294-72
[34]  
Ellams SD(2017)Large cell transformation of oral mycosis fungoides Head Neck Pathol 54 e327-315
[35]  
Reynolds WR(2015)Correlations between clinical and pathological features in 17 cases of mycosis fungoides before and after transformation Int J Dermatol 51 61-4739
[36]  
Feldman MI(1972)Mycosis fungoides. Survival, prognostic features, response to therapy, and autopsy findings Medicine 31 297-771
[37]  
Bricout PB(2017)Mycosis fungoides and Sezary syndrome Hematol Oncol Clin North Am 28 4730-831
[38]  
Potdar GG(2010)Survival outcomes and prognostic factors in mycosis fungoides/Sezary syndrome: validation of the revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer staging proposal J Clin Oncol 116 767-21
[39]  
Wright JM(2010)Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors Blood. 119 825-951
[40]  
Balciunas BA(2013)Hydrochlorothiazide and cutaneous T cell lymphoma: prospective analysis and case series Cancer. 34 15-7217