Mitochondrial dysfunction in Parkinson's disease

被引：2
|
作者：
Buneeva O.A. [1 ]
Medvedev A.E. [1 ]
机构：
[1] Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow 119121
来源：
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry | 2011年 / 5卷 / 4期
关键词：
genomics; mitochondria; mitochondrial enzymes; Parkinson's disease; proteomics;
D O I：
10.1134/S1990750811040032
中图分类号：
学科分类号：
摘要：
The review highlights mitochondrial structural and functional abnormalities in Parkinson's disease and experimental animal models of this pathology. Special attention is paid to the inactivation of mitochondrial enzymes, mutations in mitochondrial and nuclear DNA, and genomic and proteomic studies of mitochondrial proteins in Parkinson's disease and experimental parkinsonism in animals. © 2011 Pleiades Publishing, Ltd.
引用
收藏
页码：313 / 336
页数：23
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