Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma

被引：0
作者：
T. Y. S. Le Large
M. F. Bijlsma
B. El Hassouni
G. Mantini
T. Lagerweij
A. A. Henneman
N. Funel
B. Kok
T. V. Pham
R. de Haas
L. Morelli
J. C. Knol
S. R. Piersma
G. Kazemier
H. W. M. van Laarhoven
E. Giovannetti
C. R. Jimenez
机构：
[1] VU University Amsterdam,Department of Surgery, Cancer Center Amsterdam, Amsterdam University Medical Centers
[2] VU University,Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Centers
[3] University of Amsterdam,Laboratory for Experimental Oncology and Radiobiology, Cancer Center Amsterdam, Amsterdam University Medical Center
[4] VU University,OncoProteomics Laboratory, Department of Medical Oncology, Cancer, Cancer Center Amsterdam, Amsterdam University Medical Centers
[5] Oncode Institute,Cancer Pharmacology Lab, AIRC
[6] Fondazione Pisana per la Scienza,Start
[7] VU University Amsterdam,Up
[8] Azienda Ospedaliero-Universitaria Pisana,Department of Neurosurgery, Cancer Center Amsterdam, Amsterdam University Medical Centers
[9] University of Amsterdam,Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam University Medical Center
来源：
Journal of Experimental & Clinical Cancer Research | / 40卷
关键词：
Pancreatic cancer; Therapy; FAK; EPHA2; MET; Phosphoproteomics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] nab-Paclitaxel: Novel Clinical and Experimental Evidence in Pancreatic Cancer
    Neesse, A.
    Michl, P.
    Tuveson, D. A.
    Ellenrieder, V.
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2014, 52 (04): : 360 - 366
  • [32] Napabucasin plus nab-paclitaxel with gemcitabine versus nab-paclitaxel with gemcitabine in previously untreated metastatic pancreatic adenocarcinoma: an adaptive multicentre, randomised, open-label, phase 3, superiority trial
    Bekaii-Saab, Tanios
    Okusaka, Takuji
    Goldstein, David
    Oh, Do-Youn
    Ueno, Makoto
    Ioka, Tatsuya
    Fang, Weijia
    Anderson, Eric C.
    Noel, Marcus S.
    Reni, Michele
    Choi, Hye Jin
    Goldberg, Jonathan S.
    Oh, Sang Cheul
    Li, Chung-Pin
    Tabernero, Josep
    Li, Jian
    Foos, Emma
    Oh, Cindy
    Van Cutsem, Eric
    ECLINICALMEDICINE, 2023, 58
  • [33] Concurrent Nab-paclitaxel and Radiotherapy Novel Radiosensitization for Borderline Resectable or Unresectable Pancreatic Cancer
    Arscott, William T.
    Nead, Kevin T.
    Bear, Adham
    Venigalla, Sriram
    Shabason, Jacob
    Lukens, John N.
    Plastaras, John P.
    Wojcieszynski, Andrzej
    Metz, James
    O'Hara, Mark
    Reiss, Kim A.
    Teitelbaum, Ursina
    Loaiza-Bonilla, Arturo
    Drebin, Jeffrey
    Lee, Major K.
    Shroff, Stuti G.
    Ben-Josef, Edgar
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2021, 44 (09): : 469 - 474
  • [34] nab-Paclitaxel plus gemcitabine in metastatic pancreatic adenocarcinoma: Australian subset analyses of the phase III MPACT trial
    Young, Rosemary
    Mainwaring, Paul
    Clingan, Philip
    Parnis, Francis Xavier
    Asghari, Gholamreza
    Beale, Philip
    Aly, Abdalla
    Botteman, Marc
    Romano, Alfredo
    Ferrara, Stefano
    Margunato-Debay, Sandra
    Harris, Marion
    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2018, 14 (05) : e325 - e331
  • [35] FOLFIRINOX for Advanced Pancreatic Cancer Patients After Nab-Paclitaxel Plus Gemcitabine Failure
    Matsumoto, Toshihiko
    Kurioka, Yusuke
    Okazaki, Ukyo
    Matsuo, Yu
    Kimura, Shogo
    Miura, Kou
    Tsuduki, Takao
    Takagi, Shinjiro
    Takatani, Masahiro
    Morishita, Hirofumi
    PANCREAS, 2020, 49 (04) : 574 - 578
  • [36] Celecoxib synergizes human pancreatic ductal adenocarcinoma cells to sorafenib-induced growth inhibition
    Rosendahl, Ann H.
    Gundewar, Chinmay
    Said, Katarzyna
    Karnevi, Emelie
    Andersson, Roland
    PANCREATOLOGY, 2012, 12 (03) : 219 - 226
  • [37] Nab-paclitaxel plus gemcitabine for metastatic pancreatic adenocarcinoma after Folfirinox failure: an AGEO prospective multicentre cohort
    Portal, Alix
    Pernot, Simon
    Tougeron, David
    Arbaud, Claire
    Bidault, Anne Thirot
    de la Fouchardiere, Christelle
    Hammel, Pascal
    Lecomte, Thierry
    Dreanic, Johann
    Coriat, Romain
    Bachet, Jean-Baptiste
    Dubreuil, Olivier
    Marthey, Lysiane
    Dahan, Laetitia
    Tchoundjeu, Belinda
    Locher, Christophe
    Lepere, Celine
    Bonnetain, Franck
    Taieb, Julien
    BRITISH JOURNAL OF CANCER, 2015, 113 (07) : 989 - 995
  • [38] Phase I Trial of nab-Paclitaxel Administered Concurrently With Radiotherapy in Patients With Locally Advanced Inoperable Pancreatic Adenocarcinoma
    Roy, Amitesh Chandra
    Abbas, M. Nazim
    Price, Timothy Jay
    Singhal, Nimit
    Vatandoust, Sina
    Leung, John
    Kichenadasse, Ganessan
    Koczwara, Bogda
    Sukumaran, Shawgi
    Kumar, Rajiv
    Woodman, Richard
    Scott-Hoy, Alex
    Karapetis, Christos Stelios
    PANCREAS, 2022, 51 (05) : 490 - 495
  • [39] Potential Role of Exosomes in the Chemoresistance to Gemcitabine and Nab-Paclitaxel in Pancreatic Cancer
    Comandatore, Annalisa
    Immordino, Benoit
    Balsano, Rita
    Capula, Mjriam
    Garajova, Ingrid
    Ciccolini, Joseph
    Giovannetti, Elisa
    Morelli, Luca
    DIAGNOSTICS, 2022, 12 (02)
  • [40] Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma
    Kanteti, Rajani
    Mirzapoiazova, Tamara
    Riehm, Jacob J.
    Dhanasingh, Immanuel
    Mambetsariev, Bolot
    Wang, Jiale
    Kulkarni, Prakash
    Kaushik, Garima
    Seshacharyulu, Parthasarathy
    Ponnusamy, Moorthy P.
    Kindler, Hedy L.
    Nasser, Mohd W.
    Batra, Surinder K.
    Salgia, Ravi
    CANCER BIOLOGY & THERAPY, 2018, 19 (04) : 316 - 327
12345