STLV-1 as a model for studying HTLV-1 infection

被引：0
作者：
Brice Jégado
Fatah Kashanchi
Hélène Dutartre
Renaud Mahieux
机构：
[1] Ecole Normale Supérieure de Lyon,International Center for Research in Infectiology, Retroviral Oncogenesis Laboratory, INSERM U1111
[2] Université Lyon, Université Claude Bernard Lyon 1, CNRS, UMR5308
[3] Fondation pour la Recherche Médicale,Laboratory of Molecular Virology
[4] Labex Ecofect,undefined
[5] George Mason University,undefined
来源：
Retrovirology | / 16卷
关键词：
HTLV-1; STLV-1; ATL; Prevalence; Interspecies transmission; Animal model; Therapy;
D O I：
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摘要：
Few years after HTLV-1 identification and isolation in humans, STLV-1, its simian counterpart, was discovered. It then became clear that STLV-1 is present almost in all simian species. Subsequent molecular epidemiology studies demonstrated that, apart from HTLV-1 subtype A, all human subtypes have a simian homolog. As HTLV-1, STLV-1 is the etiological agent of ATL, while no case of TSP/HAM has been described. Given its similarities with HTLV-1, STLV-1 represents a unique tool used for performing clinical studies, vaccine studies as well as basic science.
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[71]  
Watanabe T(1998)Reduced transmission and prevalence of simian T-cell lymphotropic virus in a closed breeding colony of chimpanzees (Pan troglodytes verus) Virology 246 277-5291
[72]  
Seiki M(1996)High variety of different simian T-cell leukemia virus type 1 strains in chimpanzees (Pan troglodytes verus) of the Taï National Park, Côte d’Ivoire J Acquir Immune Defic Syndr Hum Retrovirol. 13 S38-514
[73]  
Hirayama Y(1986)Transmission dynamics of simian T-lymphotropic virus type 1 (STLV1) in a baboon breeding colony: predominance of female-to-female transmission Jpn J Cancer Res 77 1227-289
[74]  
Yoshida M(1986)Phylogenetic analysis of SIV and STLV type I in mandrills ( J Med Primatol 15 311-1029
[75]  
Mossoun A(1987)): indications that intracolony transmissions are predominantly the result of male-to-male aggressive contacts Cancer Res 47 269-3808
[76]  
Calvignac-Spencer S(1990)Modes of transmission of simian T-lymphotropic virus type 1 in semi-captive mandrills ( Lab Anim Sci 40 79-1639
[77]  
Anoh AE(1993)) Lab Anim Sci 43 301-378
[78]  
Pauly MS(2013)Simian T-cell lymphotropic viruses (STLVs) and lymphomas in african nonhuman primates Comp Med 63 288-266
[79]  
Driscoll DA(2013)Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1) Retrovirology 10 118-4867
[80]  
Michel AO(1984)Two new human T-lymphotropic virus type I phylogenetic subtypes in seroindeterminates, a Mbuti pygmy and a Gabonese, have closest relatives among African STLV-I strains Science 225 716-1337
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