The new triterpene glycoside cycloorbicoside C was isolated from the aerial parts of Astragalus orbiculatus Ledeb. (Leguminosae) and was identified as (23R,24S)-16β,23;16α,24-diepoxycycloartan-3β,25-diol 3-O-β-D-xylopyranoside 25-O-β-D-glucopyranoside.