Dynamic structure of membrane-anchored Arf•GTP

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作者
Yizhou Liu
Richard A Kahn
James H Prestegard
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[1] Complex Carbohydrate Research Center,Department of Biochemistry
[2] University of Georgia,undefined
[3] Emory University School of Medicine,undefined
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摘要
ARF proteins play key roles in the budding and maturation of eukaryotic transport vesicles. The high-resolution NMR structure of full-length yeast Arf1-GTP anchored to a membrane mimic reveals a flexible linker between the myristoylated N-terminal helix and the GTPase domain, which would facilitate interaction with multiple partners.
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页码:876 / 881
页数:5
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