Design and Rationale of the ARBITER 6 Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol)-6-HDL and LDL Treatment Strategies in Atherosclerosis (HALTS)

[1] de Groot E(1995)Effect of pravastatin on progression and regression of coronary atherosclerosis and vessel wall changes in carotid and femoral arteries: a report from the Regression Growth Evaluation Statin Study Am J Cardiol 76 40C-46C

[2] Jukema JW(1990)Beneficial effects of colestipol-niacin on coronary atherosclerosis. A 4-year follow-up [see comments] JAMA 264 3013-3017

[3] van Boven AJ(1996)Progression of coronary artery disease predicts clinical coronary events. Long-term follow-up from the Cholesterol Lowering Atherosclerosis Study Circulation 93 34-41

[4] Reiber JH(1993)One-year reduction and longitudinal analysis of carotid intima-media thickness associated with colestipol/niacin therapy Stroke 24 1779-1783

[5] Zwinderman AH(1990)Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B [see comments] N Engl J Med 323 1289-1298

[6] Lie KI(2001)Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease N Engl J Med 345 1583-1592

[7] Cashin-Hemphill L(2004)Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins Circulation 110 3512-3517

[8] Mack WJ(2006)The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3 Curr Med Res Opin 22 2243-2250

[9] Pogoda JM(2004)Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial JAMA 291 1071-1080

[10] Sanmarco ME(2002)ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness Circulation 106 2055-2060

[1] de Groot E(1995)Effect of pravastatin on progression and regression of coronary atherosclerosis and vessel wall changes in carotid and femoral arteries: a report from the Regression Growth Evaluation Statin Study Am J Cardiol 76 40C-46C

[2] Jukema JW(1990)Beneficial effects of colestipol-niacin on coronary atherosclerosis. A 4-year follow-up [see comments] JAMA 264 3013-3017

[3] van Boven AJ(1996)Progression of coronary artery disease predicts clinical coronary events. Long-term follow-up from the Cholesterol Lowering Atherosclerosis Study Circulation 93 34-41

[4] Reiber JH(1993)One-year reduction and longitudinal analysis of carotid intima-media thickness associated with colestipol/niacin therapy Stroke 24 1779-1783

[5] Zwinderman AH(1990)Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B [see comments] N Engl J Med 323 1289-1298

[6] Lie KI(2001)Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease N Engl J Med 345 1583-1592

[7] Cashin-Hemphill L(2004)Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins Circulation 110 3512-3517

[8] Mack WJ(2006)The effect of 24 months of combination statin and extended-release niacin on carotid intima-media thickness: ARBITER 3 Curr Med Res Opin 22 2243-2250

[9] Pogoda JM(2004)Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial JAMA 291 1071-1080

[10] Sanmarco ME(2002)ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness Circulation 106 2055-2060