The discovery of human TSLP as a critical epithelial cytokine in type 2 immunity and allergic disease

被引:9
作者
Soumelis, Vassili [1 ,2 ]
Liu, Yong-Jun [3 ]
机构
[1] Univ Paris, Inst Rech St Louis, HIPI Unit, Inserm,U976, Paris, France
[2] Hop St Louis, AP HP, Lab Immunol & Histocompatibil, Paris, France
[3] Sanofi R&D, Cambridge, MA USA
关键词
DENDRITIC CELLS; INDUCE;
D O I
10.1038/s41590-020-0720-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Working on the function of a new cytokine always makes for exciting times. Vassili Soumelis and Yong-Jun Liu bring us back to the discovery and functional characterization of human TSLP, in the very stimulating environment of the DNAX Research Institute.
引用
收藏
页码:1471 / 1473
页数:3
相关论文
共 11 条
[1]   Distinct Signal Codes Generate Dendritic Cell Functional Plasticity [J].
Arima, Kazuhiko ;
Watanabe, Norihiko ;
Hanabuchi, Shino ;
Chang, Mikyoung ;
Sun, Shao-Cong ;
Liu, Yong-Jun .
SCIENCE SIGNALING, 2010, 3 (105) :ra4
[2]   HEMATOPOIETIC RECEPTORS AND HELICAL CYTOKINES [J].
BAZAN, JF .
IMMUNOLOGY TODAY, 1990, 11 (10) :350-354
[3]   A Modular View of Cytokine Networks in Atopic Dermatitis [J].
Carmi-Levy, Irit ;
Homey, Bernhard ;
Soumelis, Vassili .
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2011, 41 (03) :245-253
[4]   Tezepelumab in Adults with Uncontrolled Asthma [J].
Corren, Jonathan ;
Parnes, Jane R. ;
Wang, Liangwei ;
Mo, May ;
Roseti, Stephanie L. ;
Griffiths, Janet M. ;
van der Merwe, Rene .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (10) :936-946
[5]   Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses [J].
Gauvreau, Gail M. ;
O'Byrne, Paul M. ;
Boulet, Louis-Philippe ;
Wang, Ying ;
Cockcroft, Donald ;
Bigler, Jeannette ;
FitzGerald, J. Mark ;
Boedigheimer, Michael ;
Davis, Beth E. ;
Dias, Clapton ;
Gorski, Kevin S. ;
Smith, Lynn ;
Bautista, Edgar ;
Comeau, Michael R. ;
Leigh, Richard ;
Parnes, Jane R. .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (22) :2102-2110
[6]   TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand [J].
Ito, T ;
Wang, YH ;
Duramad, O ;
Hori, T ;
Delespesse, GJ ;
Watanabe, N ;
Qin, FXF ;
Yao, ZB ;
Cao, W ;
Liu, YJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 202 (09) :1213-1223
[7]   Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma [J].
Mitchell, Patrick D. ;
O'Byrne, Paul M. .
PHARMACOLOGY & THERAPEUTICS, 2017, 169 :104-112
[8]   Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor [J].
Park, LS ;
Martin, U ;
Garka, K ;
Gliniak, B ;
Di Santo, JP ;
Muller, W ;
Largaespada, DA ;
Copeland, NG ;
Jenkins, NA ;
Farr, AG ;
Ziegler, SF ;
Morrissey, PJ ;
Paxton, R ;
Sims, JE .
JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (05) :659-669
[9]   Human thymic stromal lymphopoietin preferentially stimulates myeloid cells [J].
Reche, PA ;
Soumelis, V ;
Gorman, DM ;
Clifford, T ;
Liu, MR ;
Travis, M ;
Zurawski, SM ;
Johnston, J ;
Liu, YJ ;
Spits, H ;
Malefyt, RD ;
Kastelein, RA ;
Bazan, JF .
JOURNAL OF IMMUNOLOGY, 2001, 167 (01) :336-343
[10]   Human epithelial cells trigger dendritic cell-mediated allergic inflammation by producing TSLP [J].
Soumelis, V ;
Reche, PA ;
Kanzler, H ;
Yuan, W ;
Edward, G ;
Homey, B ;
Gilliet, M ;
Ho, S ;
Antonenko, S ;
Lauerma, A ;
Smith, K ;
Gorman, D ;
Zurawski, S ;
Abrams, J ;
Menon, S ;
McClanahan, T ;
de Waal-Malefyt, R ;
Bazan, F ;
Kastelein, RA ;
Liu, YJ .
NATURE IMMUNOLOGY, 2002, 3 (07) :673-680