Fluorescein angiographic features of the congenital hypertrophy of the retinal pigment epithelium in the familial adenomatous polyposis.

被引：9
作者：
Touriño R. [1 ]
Rodríguez-Ares M.T. [1 ]
López-Valladares M.J. [1 ]
Gómez-Ulla F. [1 ]
Gómez-Torreiro M. [1 ]
Capeans C. [1 ]
机构：
[1] Department of Ophthalmology, School of Medicine of Santiago de Compostela, Complejo Hospitalario Universitario de Santiago-Hospital de Conxo, La Coruña, R/Ramón Baltar s/n. 15.706, Santiago de Compostela
来源：
International Ophthalmology | 2005年 / 26卷 / 1-2期
关键词：
Fluorescein angiography; Congenital hypertrophy of the retinal pigment epithelium; Familial adenomatous polyposis; Pigmented retinal lesions;
D O I：
10.1007/s10792-006-0007-5
中图分类号：
学科分类号：
摘要：
PURPOSE: To asses the prevalence of fluorescein angiographic features in bilateral and multifocal Congenital Hypertrophy of the Retinal Pigment Epithelium (CHRPE) in patients with a diagnosis of familial adenomatous polyposis. METHODS: We performed prospective angiographic and clinical examination of 49 CHPRE lesions in 15 patients. RESULTS: About 77.5% of CHRPE lesions were close to retinal vessels. The retinal vascular changes observed overlying and surrounding the CHRPE were: capillary non-perfusion with an area greater than 0.5 disc diameters (41%), capillary microaneurysms (4%), chorioretinal anastomoses (6.2%), attenuation of retinal vessels (4%), choriocapillary vessels inside the lacunae (6.2%) and in the depigmented marginal halo (18.4%). Depigmented streaks in contact with one or both edges of the CHRPE were observed in 79.6% of the lesions. About 9.6% of the lesions were not seen on ophthalmoscopy and could only be detected by angiography. CONCLUSIONS: Even though the diagnosis of CHRPE is clinical, fluorescein angiography may be useful in confirming the diagnosis, as well as detecting additional lesions not seen by means of ophthalmoscopic examination.
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页码：59 / 65
页数：6
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