A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma

被引：0
|
作者：
Zhenyang Liu
Michael Ho-Young Ahn
Tomohiro Kurokawa
Amy Ly
Gong Zhang
Fuyou Wang
Teppei Yamada
Ananthan Sadagopan
Jane Cheng
Cristina R. Ferrone
Andrew S. Liss
Kim C. Honselmann
Gregory R. Wojtkiewicz
Soldano Ferrone
Xinhui Wang
机构：
[1] Massachusetts General Hospital,Division of Surgical Oncology, Department of Surgery
[2] Harvard Medical School,Department of Gastroenterology and Urology and of Medical Oncology
[3] Hunan Cancer Hospital,Department of Pathology
[4] Xiangya School of Medicine,Division of General and Gastrointestinal Surgery, Department of Surgery
[5] Central South University,Mouse Imaging Program, Center for Systems Biology
[6] Massachusetts General Hospital,Department of Orthopaedic Surgery
[7] Harvard Medical School,undefined
[8] Massachusetts General Hospital,undefined
[9] Harvard Medical School,undefined
[10] Massachusetts General Hospital,undefined
[11] Harvard Medical School,undefined
[12] Massachusetts General Hospital,undefined
[13] Harvard Medical School,undefined
来源：
Journal of Translational Medicine | / 18卷
关键词：
PDX expansion; Subcutaneous PDX mouse model; Orthotopic PDX mouse model; PDAC PDX;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma
    Liu, Zhenyang
    Ahn, Michael Ho-Young
    Kurokawa, Tomohiro
    Ly, Amy
    Zhang, Gong
    Wang, Fuyou
    Yamada, Teppei
    Sadagopan, Ananthan
    Cheng, Jane
    Ferrone, Cristina R.
    Liss, Andrew S.
    Honselmann, Kim C.
    Wojtkiewicz, Gregory R.
    Ferrone, Soldano
    Wang, Xinhui
    JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18 (01)
  • [2] Defining and tracing subtypes of patient-derived xenograft models in pancreatic ductal adenocarcinoma
    Hyun, Sangyeop
    Han, Youngmin
    Moon, Jae Yun
    Suh, Young-Ah
    Yun, Won-Gun
    Kwon, Wooil
    Lee, Jong-Eun
    Kim, Daeun
    Ku, Ja-Lok
    Jang, Jin-Young
    Park, Daechan
    CANCER COMMUNICATIONS, 2024, 44 (08) : 921 - 925
  • [3] Development of gemcitabine-resistant patient-derived xenograft models of pancreatic ductal adenocarcinoma
    Miller, Aubrey L.
    Garcia, Patrick L.
    Gamblin, Tracy L.
    Vance, Rebecca B.
    Yoon, Karina J.
    CANCER DRUG RESISTANCE, 2020, 3 (03) : 572 - 585
  • [4] Characterization of a collection of patient-derived xenograft models for pancreatic ductal adenocarcinoma translational research
    Yanez, Mariana
    Arenas, Enrique Javier
    Macarulla, Teresa
    Tian, Tian
    Arribas, Joaquin
    Llorente, Sofia
    Fabregat, Carles
    Escorihuela, Marta
    Castet, Florian
    Querol, Jessica
    Salcedo, Maria Teresa
    CANCER RESEARCH, 2024, 84 (02)
  • [5] Acoustic Cluster Therapy enhances the efficacy of chemotherapeutic regimens in patient-derived xenograft mouse models for pancreatic ductal adenocarcinoma
    Ng, Serina
    Healey, Andrew
    Kvale, Svein
    Kotopoulis, Spiros
    Von Hoff, Daniel D.
    Sontum, Per Christian
    Han, Haiyong
    MOLECULAR CANCER THERAPEUTICS, 2019, 18 (12)
  • [6] Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient-derived xenograft models
    Anastasia, Alessia
    Formenti, Laura
    Ostano, Paola
    Minoli, Lucia
    Resovi, Andrea
    Morosi, Lavinia
    Fioravanti, Claudia
    Micotti, Edoardo
    Matteo, Cristina
    Scanziani, Eugenio
    Chiorino, Giovanna
    Giavazzi, Raffaella
    Ghilardi, Carmen
    Belotti, Dorina
    MOLECULAR ONCOLOGY, 2025,
  • [7] Isolation and Characterization of Patient-derived Pancreatic Ductal Adenocarcinoma Organoid Models
    Tiriac, Herve
    French, Randall
    Lowy, Andrew
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2020, (155):
  • [8] Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models
    Inkoom, Andriana
    Ndemazie, Nkafu
    Affram, Kevin
    Smith, Taylor
    Zhu, Xue
    Underwood, Patrick
    Krishnan, Sunil
    Ofori, Edward
    Han, Bo
    Trevino, Jose
    Agyare, Edward
    INTERNATIONAL JOURNAL OF PHARMACEUTICS-X, 2020, 2
  • [9] Circulating Tumor Cells as a Biomarker of Response to Treatment in Patient-Derived Xenograft Mouse Models of Pancreatic Adenocarcinoma
    Torphy, Robert J.
    Tignanelli, Christopher J.
    Kamande, Joyce W.
    Moffitt, Richard A.
    Loeza, Silvia G. Herrera
    Soper, Steven A.
    Yeh, Jen Jen
    PLOS ONE, 2014, 9 (02):
  • [10] Expression of Hedgehog pathway molecules in patient-derived pancreatic adenocarcinoma xenograft models
    Vuarogueaux, Vincent
    Misters, Simon
    Fiebig, Heinz-Herbert
    Foucault, Frederic
    Beckers, Thomas
    CANCER RESEARCH, 2011, 71
12345