Integrating tumor microenvironment with cancer molecular classifications

被引:0
作者
Etienne Becht
Aurélien de Reyniès
Wolf H. Fridman
机构
[1] INSERM UMR_S 1138,
[2] Cancer,undefined
[3] Immune Control and Escape,undefined
[4] Cordeliers Research Centre,undefined
[5] Université Paris Descartes,undefined
[6] Université Pierre et Marie Curie,undefined
[7] Programme Cartes d’Identité des Tumeurs,undefined
[8] Ligue Nationale Contre le Cancer,undefined
来源
Genome Medicine | / 7卷
关键词
Immune Checkpoint; Checkpoint Inhibitor; Molecular Subgroup; Immune Microenvironment; Suppressive Myeloid Cell;
D O I
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中图分类号
学科分类号
摘要
The composition of the tumor microenvironment is associated with a patient's prognosis and can be therapeutically targeted. A link between the cellular composition and genomic features of the tumor and its response to immunotherapy is beginning to emerge. Analyzing the microenvironment of tumor molecular subgroups can be a useful approach to tailor immunotherapies.
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