Pharmacoproteomics in drug development

被引：0
作者：
Frank A Witzmann
Raymond A Grant
机构：
[1] Indiana University School of Medicine,Department of Cellular and Integrative Physiology
[2] The Procter & Gamble Company,Corporate Research
来源：
The Pharmacogenomics Journal | 2003年 / 3卷
关键词：
drug development; mass spectrometry; protein array; protein interactions; proteomics; toxicology; two-dimensional electrophoresis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The field of proteomics is taking on increased significance as the relevance of investigating and understanding protein expression in disease and drug development is appreciated. Recent advances in proteomics have been driven by the availability of numerous annotated whole-genome sequences and a broad range of technological and bioinformatic developments that underscore the complexity of the proteome. This review briefly addresses some of the various technologies that comprise Expression Proteomics and Functional Proteomics, citing examples where these emerging approaches have been applied to pharmacology, toxicology, and the development of drugs.
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页码：69 / 76
页数：7
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