Genetic epidemiological approaches in the study of risk factors for cardiovascular disease

被引：7
作者：
Iliadou A. [1 ,4 ]
Snieder H. [2 ,3 ]
机构：
[1] Dept. of Med. Epidemiol./Biostatist., Karolinska Institute, Stockholm
[2] Georgia Prevention Institute, Department of Pediatrics, Medical College of Georgia, Augusta, GA
[3] Twin Res. and Genetic Epidemiol. U., St. Thomas' Hospital, London
[4] Department of Medical Epidemiology, Karolinska Institutet, Box 281
来源：
European Journal of Epidemiology | 2004年 / 19卷 / 3期
关键词：
Association; Familial aggregation; Genetic epidemiology; Genetic linkage; Segregation;
D O I：
10.1023/B:EJEP.0000020399.19615.6c
中图分类号：
学科分类号：
摘要：
The importance of genetic factors for the susceptibility to disease has been widely recognized in the last years. Genes have been identified for monogenic diseases and the challenge lying ahead is the identification of genetic components of importance and the environments in which they are expressed for complex diseases, that is, multiple genetic factors act and interact with each other or environmental factors to add to the complexity. This paper gives a brief overview of some genetic epidemiological approaches, concepts and recent methodological developments related to the study of risk factors for cardiovascular disease in twin and family studies.
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页码：209 / 217
页数：8
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