The Calcineurin Inhibitor-Sparing (CIS) Trial - individualised calcineurin-inhibitor treatment by immunomonitoring in renal allograft recipients: protocol for a randomised controlled trial

被引:0
作者
Claudia Sommerer
Matthias Schaier
Christian Morath
Vedat Schwenger
Geraldine Rauch
Thomas Giese
Martin Zeier
机构
[1] University Hospital Heidelberg,Department of Nephrology
[2] University of Heidelberg,Institute of Medical Biometry and Informatics
[3] University Hospital Heidelberg,Department of Immunology
来源
Trials | / 15卷
关键词
Immunomonitoring; Renal transplantation; Calcineurin inhibitor; Ciclosporin A; Gene expression; CIS study; Minimisation; Immunosuppression; NFAT;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 314 条
[1]  
Meier-Kriesche HU(2006)Immunosuppression: evolution in practice and trends, 1994-2004 Am J Transplant 6 1111-1131
[2]  
Li S(2000)Improved graft survival after renal transplantation in the United States, 1988 to 1996 N Engl J Med 342 605-612
[3]  
Gruessner RW(2006)Cardiovascular complications after renal transplantation and their prevention Transplantation 82 603-611
[4]  
Fung JJ(2012)Progression of coronary artery calcification and thoracic aorta calcification in kidney transplant recipients Am J Kidney Dis 59 258-269
[5]  
Bustami RT(2003)The natural history of chronic allograft nephropathy N Engl J Med 349 2326-2333
[6]  
Barr ML(2011)Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial Lancet 377 837-847
[7]  
Leichtman AB(2013)Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study Am J Transplant 13 2875-2883
[8]  
Hariharan S(2013)Incidence and impact of de novo donor-specific alloantibody in primary renal allografts Transplantation 95 410-417
[9]  
Johnson CP(2007)Reduced exposure to calcineurin inhibitors in renal transplantation N Engl J Med 357 2562-2575
[10]  
Bresnahan BA(2010)Pharmacokinetics and pharmacodynamics of intensified versus standard dosing of mycophenolate sodium in renal transplant patients Clin J Am Soc Nephrol 5 503-511