Effect of Glucocorticoid Receptor Blockade on Analgesic Effect of Corticotropin-Releasing Factor

被引：0
作者：
N. I. Yarushkina
T. R. Bagaeva
L. P. Filaretova
机构：
[1] I. P. Pavlov Institute of Physiology,Laboratory of Experimental Endocrinology
[2] Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2011年 / 150卷
关键词：
corticotropin-releasing factor; corticosterone; glucocorticoid receptors; pain sensitivity; rats;
D O I：
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中图分类号：
学科分类号：
摘要：
The role of glucocorticoid receptors in the analgesic effect of corticotropin-releasing factor in rats was studied after glucocorticoid receptor blockade with antagonist RU 38486. Glucocorticoid hormones can potentiate the analgesic effect of corticotropin-releasing factor or modulate the mechanisms of this effect, which depends on the type of painful stimulus.
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页码：579 / 582
页数：3
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