Encephalopathy induced by levetiracetam in an elderly woman

被引：0
作者：
Caroline Hommet
Emilie Beaufils
Vincent Roubeau
Bertrand De Toffol
Héliette Ripault
Thierry Constans
Karl Mondon
机构：
[1] University Hospital of Tours,Geriatric Department
[2] University F Rabelais,undefined
[3] UMR Inserm U 930,undefined
[4] Neurology,undefined
[5] University Hospital of Tours,undefined
来源：
Aging Clinical and Experimental Research | 2013年 / 25卷
关键词：
Elderly; Encephalopathy; Epilepsy; Levetiracetam;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Levetiracetam is frequently used in the elderly considering its favorable pharmacological profile, efficacy, and good tolerance. We reported an encephalopathy with levetiracetam in an elderly subject who had no renal failure, no concomitant valproate medication, and no other additional co-morbidities. Levetiracetam should be discontinued when this condition is suspected.
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页码：111 / 113
页数：2
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共 41 条
[1]  
Folstein MF(1975)“Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 189-198
[2]  
Folstein SE(2011)Geriatric epilepsy: research and clinical directions for the future Epilepsy Behav 22 103-111
[3]  
McHugh PR(2008)Levetiracetam efficacy in idiopathic generalized epilepsy: long suspected and now confirmed in randomized clinical trials Epilepsy Curr 8 16-18
[4]  
Roberson ED(2011)The safety and efficacy of add-on levetiracetam in elderly patients with focal epilepsy: a one-year observational study Seizure 20 305-311
[5]  
Hope OA(2009)Epilepsy in later life Lancet Neurol 8 1019-1030
[6]  
Martin RC(2010)Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy Arch Neurol 67 408-415
[7]  
Schmidt D(1996)Seizure-inducing effects of antiepileptic drugs: a review Acta Neurol Scand 94 367-377
[8]  
Abou-Khalil BW(2000)Valproate-induced hyperammonemic encephalopathy in the presence of topiramate Neurology 54 230-232
[9]  
Werhahn KJ(1988)Valproic acid encephalopathy J Epilepsy 1 197-202
[10]  
Klimpe S(2002)Valproate-induced hyperammonemic encephalopathy Metab Brain Dis 17 367-373
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